SCHEMBL6556364

SCHEMBL6556364

CCCC(=O)Oc1cccc(F)c1

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 5/20 0.48
ALDH1A1 P00352 3/20 0.48
MEN1 O00255 2/20 0.48
HPGD P15428 1/20 0.48
BCL9 O00512 1/20 0.46
CTNNB1 P35222 1/20 0.46
ACHE P22303 1/20 0.46
KDM4E B2RXH2 1/20 0.46
GLA P06280 1/20 0.46
GAA P10253 1/20 0.46
ESR1 P03372 1/20 0.45
ESR2 Q92731 1/20 0.45
PDGFRB P09619 1/20 0.45
PDGFRA P16234 1/20 0.45
PPARG P37231 1/20 0.43
PPARA Q07869 1/20 0.43
MRGPRX4 Q96LA9 1/20 0.43
SMN1; SMN2 Q16637 1/20 0.42
LMNA P02545 1/20 0.42
MAPK1 P28482 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10711104 0.90 KMT2A (0.49) KMT2AALDH1A1MEN1HPGDACHE
SCHEMBL421378 0.88 BCL9 (0.53) KMT2AALDH1A1MEN1BCL9CTNNB1
SCHEMBL29852392 0.86 ACHE (0.61) KMT2AALDH1A1MEN1HPGDACHE
SCHEMBL1021094 0.86 ACHE (0.61) KMT2AALDH1A1MEN1HPGDACHE
SCHEMBL27530747 0.84 PPARG (0.41) KMT2AALDH1A1MEN1HPGDESR1
SCHEMBL1290274 0.84 ESR1 (0.43) KMT2AALDH1A1MEN1HPGDACHE
SCHEMBL4810160 0.83 LMNA (0.62) KMT2AALDH1A1BCL9CTNNB1ACHE
SCHEMBL2000269 0.82 BCL9 (0.47) KMT2AALDH1A1BCL9CTNNB1KDM4E
SCHEMBL15763906 0.82 MEN1 (0.52) KMT2AALDH1A1MEN1HPGDACHE
SCHEMBL1820340 0.81 MTNR1B (0.55) LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 24 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3523280-B1 PROCESSES AND INTERMEDIATES FOR PREPARING A BTK INHIBITOR JANSSEN PHARMACEUTICA NV (BE) 2026-03-11 EP claimed
CN-103502213-B Alkaloid ester and carbamate derivatives thereof and medicinal compositions 奇斯药制品公司 2016-09-28 CN disclosed
CN-103748075-B 2,3-diphenyl valeronitrile derivant, its preparation method and as herbicide and the purposes of plant growth regulator 拜耳知识产权有限责任公司 2016-09-07 CN disclosed
CN-104112870-A Nonaqueous electrolyte solution and nonaqueous electrolyte battery using same MITSUBISHI CHEM CORP 2014-10-22 CN disclosed
US-20130244122-A1 NONAQUEOUS ELECTROLYTIC SOLUTION AND NONAQUEOUS-ELECTROLYTE BATTERY EMPLOYING THE SAME ONUKI MASAMICHI (JP) 2013-09-19 US disclosed
US-20120219866-A1 NONAQUEOUS ELECTROLYTIC SOLUTION AND NONAQUEOUS-ELECTROLYTE BATTERY EMPLOYING THE SAME MITSUBISHI CHEMICAL CORPORATION (JP) 2012-08-30 US disclosed
EP-2475041-A1 NON-AQUEOUS ELECTROLYTIC SOLUTION, AND NON-AQUEOUS ELECTROLYTE BATTERY COMPRISING SAME Mitsubishi Chemical Corporation (JP) 2012-07-11 EP disclosed
CN-102484281-A Nonaqueous electrolyte solution and nonaqueous electrolyte battery using same MITSUBISHI CHEM CORP 2012-05-30 CN disclosed
CN-1260266-C Poly(hydroxy alkanoate), its preparation method and use of microbe in its preparation CANON KK (JP) 2006-06-21 CN disclosed
CN-1633434-A Imidazo [1, 2-a ] pyridine derivatives DAIICHI SEIYAKU CO (JP) 2005-06-29 CN disclosed
EP-1087959-A1 NOVEL BENZOPYRAN OR THIOBENZOPYRAN DERIVATIVES CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) 2001-04-04 EP disclosed
EP-1042275-A1 ANTICONVULSANT AND CENTRAL NERVOUS SYSTEM-ACTIVE BIS(FLUOROPHENYL)ALKYLAMIDES NPS PHARMACEUTICALS, INC. (US) 2000-10-11 EP disclosed
WO-1999065893-A1 NOVEL BENZOPYRAN OR THIOBENZOPYRAN DERIVATIVES C & C RESEARCH LABORATORIES (KR) 1999-12-23 WO disclosed
EP-0958285-A1 TRICYCLIC BENZO[e]ISOINDOLES AND BENZO[h]ISOQUINOLINES F.HOFFMANN-LA ROCHE AG (CH) 1999-11-24 EP disclosed
WO-1999029657-A1 ANTICONVULSANT AND CENTRAL NERVOUS SYSTEM-ACTIVE BIS(FLUOROPHENYL)ALKYLAMIDES NPS PHARMACEUTICALS, INC. (US) 1999-06-17 WO disclosed
WO-1998030546-A1 TRICYCLIC BENZO[e]ISOINDOLES AND BENZO[h]ISOQUINOLINES F. HOFFMANN-LA ROCHE AG (CH) 1998-07-16 WO disclosed
US-4435419-A Method of treating depression using azabicyclohexanes AMERICAN CYANAMID COMPANY (US) 1984-03-06 US disclosed
US-4231935-A ANXIOLYTICS AND ANALGESICS AMERICAN CYANAMID COMPANY (US) 1980-11-04 US disclosed
US-4196120-A 1,2-BIS(HYDROCARBYLSULFONYLOXY OR HALO METHYL)CYCLOPROPYLBENZENE, OPTICAL ACITIVITY ANALGESICS AMERICAN CYANAMID COMPANY (US) 1980-04-01 US disclosed
US-4131611-A ANXIOLYTIC, ANALGESIC AMERICAN CYANAMID COMPANY (US) 1978-12-26 US disclosed