Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 1/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | FAAH | O00519 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.39 |
| ▸ | KCNH3 | Q9ULD8 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.35 |
| ▸ | HRH1 | P35367 | 1/20 | 0.35 |
| ▸ | MIF | P14174 | 1/20 | 0.35 |
| ▸ | ESR1 | P03372 | 2/20 | 0.34 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.34 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.34 |
| ▸ | TACR2 | P21452 | 2/20 | 0.34 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.34 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.34 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18783298 | 0.98 | KCNH2 (0.50) | KCNH2CYP2D6TDP1L3MBTL1FAAH | |
| SCHEMBL9513948 | 0.98 | KCNH2 (0.50) | KCNH2CYP2D6TDP1L3MBTL1FAAH | |
| SCHEMBL22308364 | 0.98 | KCNH2 (0.50) | KCNH2CYP2D6TDP1L3MBTL1FAAH | |
| SCHEMBL27648727 | 0.98 | KCNH2 (0.50) | KCNH2CYP2D6TDP1L3MBTL1FAAH | |
| SCHEMBL7897858 | 0.94 | CYP2D6 (0.46) | KCNH2CYP2D6TDP1L3MBTL1FAAH | |
| SCHEMBL805513 | 0.85 | — | — | |
| SCHEMBL30481644 | 0.81 | KCNH2 (0.44) | KCNH2CYP2D6TDP1L3MBTL1CYP3A4 | |
| SCHEMBL9035524 | 0.80 | KCNH3 (0.36) | CYP2D6KCNH3HSP90AA1HRH1NAAA | |
| SCHEMBL30481608 | 0.79 | KCNH2 (0.47) | KCNH2CYP2D6TDP1L3MBTL1CYP3A4 | |
| SCHEMBL31036117 | 0.78 | HRH1 (0.38) | CYP2D6KCNH3SMN1; SMN2HSP90AA1HRH1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 110 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106083936-A | Organometallic complex, light-emitting component, light-emitting device, electronic equipment and illuminator | 株式会社半导体能源研究所 | 2016-11-09 | — | — | CN | claimed |
| JP-6100544-A | — | — | None | — | — | JP | disclosed |
| JP-5320142-A | — | — | None | — | — | JP | disclosed |
| CN-115124475-B | Pyrimidine derivative and preparation method and application thereof | 贵阳学院 | 2023-11-10 | — | — | CN | disclosed |
| JP-2023126333-A | LIGHT-EMITTING MATERIAL, LIGHT-EMITTING DEVICE, AND MATERIAL FOR VAPOR DEPOSITION | 株式会社半導体エネルギー研究所 | 2023-09-07 | — | — | JP | disclosed |
| EP-3301088-B1 | CONDENSED PYRIDINES AS ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES | UNIVERSAL DISPLAY CORP (US) | 2023-08-30 | — | — | EP | disclosed |
| US-11413682-B2 | Method for producing surface-modified metal oxide fine particle, method for producing improved metal oxide fine particles, surface-modified metal oxide fine particles, and metal oxide fine particle dispersion liquid | TOKYO OHKA KOGYO CO., LTD. (JP) | 2022-08-16 | — | — | US | disclosed |
| US-11261163-B2 | Cyanopyrimidine derivatives | MERCK PATENT GMBH (DE) | 2022-03-01 | — | — | US | disclosed |
| EP-3433236-B1 | CYANOPYRIMIDINE DERIVATIVES SUITABLE AS COMPONENTS IN LIQUID CRYSTAL MEDIA | MERCK PATENT GMBH (DE) | 2021-10-27 | — | — | EP | disclosed |
| CN-107074896-B | Electroluminescent imidazoquinoxaline carbene metal complexes | UDC 爱尔兰有限责任公司 | 2021-04-13 | — | — | CN | disclosed |
| US-5002951-A | 2-amino-5-halo-4-pyrimidinol for bactericides and antiprotozoa agent | THE UPJOHN COMPANY (US) | 1991-03-26 | — | — | US | disclosed |
| US-4795812-A | ANTITUMOR | THE UPJOHN COMPANY (US) | 1989-01-03 | — | — | US | disclosed |
| US-4665077-A | IMMUNOREGULATORY AGENTS | THE UPJOHN COMPANY (US) | 1987-05-12 | — | — | US | disclosed |
| EP-0210228-A1 | 4-SUBSTITUTED-6-ARYL PYRIMIDINE COMPOUNDS | THE UPJOHN COMPANY (US) | 1987-02-04 | — | — | EP | disclosed |
| US-4619933-A | 6-aryl pyrimidines for treating aplastic anemia | THE UPJOHN COMPANY (US) | 1986-10-28 | — | — | US | disclosed |
| WO-1986004583-A1 | 4-SUBSTITUTED-6-ARYL PYRIMIDINE COMPOUNDS | THE UPJOHN COMPANY (US) | 1986-08-14 | — | — | WO | disclosed |
| US-4543248-A | Method for immunoregulation with 6-aryl pyrimidine compounds | THE UPJOHN COMPANY (US) | 1985-09-24 | — | — | US | disclosed |
| US-4507302-A | Method for treating arthritis with 6-aryl pyrimidine compounds | THE UPJOHN COMPANY (US) | 1985-03-26 | — | — | US | disclosed |
| US-4166869-A | Use of certain acyl-pyrimidines as flavouring agents | FIRMENICH, S.A. (CH) | 1979-09-04 | — | — | US | disclosed |
| US-3950525-A | BRONCHODILATION, 4-HYDROXY-6-ARYL PYRIMIDINES | PFIZER INC. (US) | 1976-04-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11261163-B2 | Cyanopyrimidine derivatives | MCM6, MCM4, MCM2 | KCNH2 876/4885CYP2D6 400/4885TDP1 428/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.