Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.49 |
| ▸ | NPC1 | O15118 | 4/20 | 0.49 |
| ▸ | RAB9A | P51151 | 4/20 | 0.49 |
| ▸ | MAPT | P10636 | 4/20 | 0.49 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.49 |
| ▸ | NFKB2 | Q00653 | 2/20 | 0.49 |
| ▸ | RELA | Q04206 | 2/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | ATM | Q13315 | 1/20 | 0.48 |
| ▸ | TP53 | P04637 | 3/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | HPGD | P15428 | 2/20 | 0.47 |
| ▸ | STAT1 | P42224 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | TOP2A | P11388 | 1/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11248352 | 0.85 | SMN1; SMN2 (0.52) | SMN1; SMN2NPC1RAB9AMAPTNFKB1 | |
| SCHEMBL6557153 | 0.83 | TOP2A (0.52) | RAB9AALDH1A1KDM4ETOP2AL3MBTL1 | |
| SCHEMBL2778627 | 0.76 | KMT2A (0.50) | NPC1RAB9AMAPTALDH1A1LMNA | |
| SCHEMBL30357748 | 0.76 | KMT2A (0.50) | NPC1RAB9AMAPTALDH1A1LMNA | |
| Alcohol SCHEMBL29004585 | 0.75 | TOP2A (0.52) | RAB9ATOP2ACYP1A2L3MBTL1 | |
| SCHEMBL11249360 | 0.75 | MAPT (0.57) | SMN1; SMN2NPC1RAB9AMAPTALDH1A1 | |
| SCHEMBL6200113 | 0.75 | CCR6 (0.54) | NPC1RAB9AMAPTALDH1A1LMNA | |
| SCHEMBL11666684 | 0.75 | ALDH1A1 (0.64) | SMN1; SMN2NPC1RAB9AMAPTNFKB1 | |
| SCHEMBL9814048 | 0.74 | KMT2A (0.51) | NPC1RAB9AMAPTALDH1A1LMNA | |
| SCHEMBL10517750 | 0.74 | MAPT (0.50) | SMN1; SMN2NPC1RAB9AMAPTNFKB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1423691-A1 | FLUORESCENCE BASED OXYGEN SENSOR SYSTEMS | 3M Innovative Properties Company (US) | 2004-06-02 | — | — | EP | disclosed |
| US-6664111-B2 | The detector is a solid polymeric matrix, e.g., siloxane, modified by a luminescent platinum group metal phenanthroline chelate complex which is quenchable by oxygen; blood and tissue samples; medical diagnosis; compact; lightweight | 3M INNOVATIVE PROPERTIES COMPANY | 2003-12-16 | — | — | US | disclosed |
| US-20030099574-A1 | Fluorescence based oxygen sensor systems | 3M INNOVATIVE PROPERTIES COMPANY | 2003-05-29 | — | — | US | disclosed |
| WO-2003019179-A1 | FLUORESCENCE BASED OXYGEN SENSOR SYSTEMS | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2003-03-06 | — | — | WO | disclosed |