Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | APEX1 | P27695 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.41 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.41 |
| ▸ | NR4A3 | Q92570 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.39 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.37 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.37 |
| ▸ | PPARG | P37231 | 2/20 | 0.36 |
| ▸ | PPARA | Q07869 | 2/20 | 0.36 |
| ▸ | CNR2 | P34972 | 2/20 | 0.36 |
| ▸ | CNR1 | P21554 | 1/20 | 0.36 |
| ▸ | THRB | P10828 | 1/20 | 0.36 |
| ▸ | HCAR2 | Q8TDS4 | 2/20 | 0.35 |
| ▸ | PLA2G2D | Q9UNK4 | 1/20 | 0.35 |
| ▸ | MTNR1A | P48039 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6556950 | 0.93 | POLB (0.45) | POLBAPEX1HTTTDP1NR4A1 | |
| SCHEMBL6554766 | 0.88 | NR4A1 (0.43) | POLBAPEX1HTTTDP1NR4A1 | |
| SCHEMBL5266032 | 0.80 | CYP1A2 (0.48) | POLBAPEX1HTTTDP1CYP1A2 | |
| SCHEMBL5174032 | 0.80 | POLB (0.45) | POLBAPEX1HTTTDP1PPARG | |
| SCHEMBL18194861 | 0.79 | THRB (0.44) | POLBAPEX1HTTTDP1CYP1A2 | |
| SCHEMBL6280134 | 0.78 | WDR5 (0.44) | POLBAPEX1HTTTDP1NR4A1 | |
| SCHEMBL1535476 | 0.77 | TDP1 (0.47) | POLBAPEX1HTTTDP1THRB | |
| SCHEMBL11963930 | 0.77 | HTT (0.42) | POLBAPEX1HTTTDP1NR4A1 | |
| Phthalic Acid SCHEMBL4599263 | 0.77 | TDP1 (0.51) | POLBAPEX1HTTTDP1THRB | |
| SCHEMBL28186333 | 0.76 | APP (0.46) | POLBAPEX1HTTTDP1THRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0843184-B1 | Ocular lens material | MENICON CO LTD (JP) | 2004-03-03 | — | — | EP | disclosed |
| US-5811502-A | CONTAINING COPOLYMERS OF METHACRYLIC ESTERS AND HAVING OXYGEN PERMEABILITY, SUFFICIENT HARDNESS AND WETTABILITY | MENICON CO., LTD. (JP) | 1998-09-22 | — | — | US | disclosed |
| EP-0843184-A2 | Ocular lens material | Menicon Co., Ltd. (JP) | 1998-05-20 | — | — | EP | disclosed |