Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR4A1 | P22736 | 1/20 | 0.43 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.43 |
| ▸ | NR4A3 | Q92570 | 1/20 | 0.43 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | APEX1 | P27695 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | MRGPRX4 | Q96LA9 | 2/20 | 0.37 |
| ▸ | PLA2G2D | Q9UNK4 | 1/20 | 0.36 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.36 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.36 |
| ▸ | CDC25B | P30305 | 1/20 | 0.36 |
| ▸ | SOS1 | Q07889 | 1/20 | 0.36 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.36 |
| ▸ | CNR2 | P34972 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6556953 | 0.88 | POLB (0.41) | NR4A1NR4A2NR4A3PTPN1POLB | |
| SCHEMBL6556950 | 0.85 | POLB (0.45) | NR4A1NR4A2NR4A3PTPN1ALDH1A1 | |
| SCHEMBL13609729 | 0.84 | CYP1A2 (0.50) | ALDH1A1CYP1A2CYP2D6CYP2C19MRGPRX4 | |
| SCHEMBL29503741 | 0.84 | CYP1A2 (0.50) | ALDH1A1CYP1A2CYP2D6CYP2C19MRGPRX4 | |
| SCHEMBL4349486 | 0.82 | MTNR1A (0.40) | CYP1A2CYP2D6CYP2C19MTNR1A | |
| SCHEMBL14001874 | 0.81 | TBXAS1 (0.37) | PTPN1ALDH1A1CACNA1BTBXAS1CDC25B | |
| SCHEMBL2619047 | 0.79 | TACR1 (0.47) | ALDH1A1CYP1A2CACNA1B | |
| SCHEMBL29503697 | 0.79 | TACR1 (0.47) | ALDH1A1CYP1A2CACNA1B | |
| SCHEMBL1324374 | 0.79 | CA2 (0.43) | ALDH1A1POLBAPEX1HTTTDP1 | |
| SCHEMBL15020207 | 0.78 | TACR1 (0.43) | ALDH1A1CYP1A2CACNA1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0843184-B1 | Ocular lens material | MENICON CO LTD (JP) | 2004-03-03 | — | — | EP | disclosed |
| US-5811502-A | CONTAINING COPOLYMERS OF METHACRYLIC ESTERS AND HAVING OXYGEN PERMEABILITY, SUFFICIENT HARDNESS AND WETTABILITY | MENICON CO., LTD. (JP) | 1998-09-22 | — | — | US | disclosed |
| EP-0843184-A2 | Ocular lens material | Menicon Co., Ltd. (JP) | 1998-05-20 | — | — | EP | disclosed |