SCHEMBL6557065

SCHEMBL6557065

CC=Cc1ccc(O)c(C=CC)c1

nearest known ligand 0.67

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CNR2 P34972 1/20 0.67
TYR P14679 1/20 0.58
LCK P06239 4/20 0.48
PELI1 Q96FA3 4/20 0.45
ALOX5 P09917 2/20 0.44
NQO2 P16083 2/20 0.42
CYP3A4 P08684 2/20 0.41
IAPP P10997 1/20 0.41
PTGS1 P23219 1/20 0.41
ATM Q13315 1/20 0.41
ALOX12 P18054 2/20 0.41
RGS12 O14924 1/20 0.41
TP53 P04637 1/20 0.41
CYP1A2 P05177 1/20 0.41
CYP2C9 P11712 1/20 0.41
PKM P14618 1/20 0.41
ALOX15 P16050 1/20 0.41
CASP1 P29466 1/20 0.41
THPO P40225 1/20 0.41
GNAI1 P63096 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9307956 0.86 TRPA1 (0.50) CNR2TYRLCKPELI1ALOX5
SCHEMBL9307948 0.86 TRPA1 (0.50) CNR2TYRLCKPELI1ALOX5
SCHEMBL4466967 0.86 CNR2 (0.60) CNR2TYRLCKPELI1IAPP
SCHEMBL13469126 0.86 CNR2 (0.60) CNR2TYRLCKPELI1IAPP
SCHEMBL30433974 0.82 LCK (0.73) CNR2TYRLCKALOX5NQO2
SCHEMBL152686 0.82 LCK (0.73) CNR2TYRLCKALOX5NQO2
SCHEMBL9746195 0.82 LCK (0.73) CNR2TYRLCKALOX5NQO2
SCHEMBL328541 0.82 LCK (0.73) CNR2TYRLCKALOX5NQO2
SCHEMBL21841320 0.80 CNR2 (1.00) CNR2TYRLCKPELI1ALOX5
SCHEMBL3949848 0.80 ALOX5 (0.57) CNR2TYRPELI1ALOX5

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1214327-B1 BLOCKED PHENYLALKYL SILANES CROMPTON CORP (US) 2004-02-25 EP disclosed
US-6559329-B2 Deblocking of a trialkoxysilane compound acontaining carbonate or acetooxy group is done by hydrolysis or alcoholyis CROMPTON CORPORATION 2003-05-06 US disclosed
US-6413646-B1 Blocked phenolic silanes CROMPTON CORPORATION 2002-07-02 US disclosed
EP-1214327-A1 BLOCKED PHENOLIC SILANES Crompton Corporation (US) 2002-06-19 EP disclosed
US-20020051890-A1 Blocked phenolic silanes WITCO CORPORATION 2002-05-02 US disclosed
US-6190833-B1 (A) A PHENOL RESIN, (B) AN AMINO RESIN, (C) A COMPOUND HAVING TWO OR MORE CROSSLINKING GROUPS IN A MOLECULE, AND (D) A HALOMETHYL-1,3,5-TRIAZINE COMPOUND. JSR CORPORATION (JP) 2001-02-20 US disclosed
WO-2001009145-A1 BLOCKED PHENOLIC SILANES CROMPTON CORPORATION (US) 2001-02-08 WO disclosed
US-6048666-A LIGHT SENSITIVE RESINS, CROSSLINKING, RUBBERS AND EPOXY COMPOUNDS FOR MULTILAYER CIRCUIT BOARDS JSR CORPORATION (JP) 2000-04-11 US disclosed