SCHEMBL9307948

SCHEMBL9307948

C=Cc1ccc(O)c(/C=C\C)c1

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TRPA1 O75762 1/20 0.50
CNR2 P34972 1/20 0.50
ALOX5 P09917 3/20 0.48
TYR P14679 1/20 0.44
ESR1 P03372 1/20 0.41
ESR2 Q92731 1/20 0.41
LCK P06239 2/20 0.39
PELI1 Q96FA3 4/20 0.39
ALDH1A1 P00352 2/20 0.37
GABRA1 P14867 1/20 0.36
GABRB2 P47870 1/20 0.36
TDP1 Q9NUW8 2/20 0.36
KDM4E B2RXH2 1/20 0.36
EGFR P00533 1/20 0.36
POLB P06746 1/20 0.36
GAA P10253 1/20 0.36
MAPT P10636 1/20 0.36
PKM P14618 1/20 0.36
L3MBTL1 Q9Y468 1/20 0.36
BACE1 P56817 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9307956 1.00 TRPA1 (0.50) TRPA1CNR2ALOX5TYRESR1
SCHEMBL6557065 0.86 CNR2 (0.67) CNR2ALOX5TYRLCKPELI1
SCHEMBL465532 0.81 TRPA1 (0.53) TRPA1CNR2ALOX5ESR1ESR2
SCHEMBL4310034 0.77 TRPA1 (0.42) TRPA1ESR1ESR2LCKPELI1
SCHEMBL17282554 0.76 TRPA1 (0.48) TRPA1CNR2ALOX5ESR1ESR2
SCHEMBL10595788 0.76 ERN1 (0.53) TRPA1ESR1ESR2KDM4E
SCHEMBL3949848 0.75 ALOX5 (0.57) CNR2ALOX5TYRESR1ESR2
SCHEMBL69994 0.75 ALDH1A1 (0.55) CNR2ALOX5ESR1ESR2LCK
SCHEMBL3949851 0.75 ALOX5 (0.57) CNR2ALOX5TYRESR1ESR2
SCHEMBL69993 0.75 ALDH1A1 (0.55) CNR2ALOX5ESR1ESR2LCK

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5376498-A Blend of an alkali-soluble resin, compound that generates an acid upon irradiation, functional aromatic compound and a phenolic compound JAPAN SYNTHETIC RUBBER CO., LTD. (JP) 1994-12-27 US disclosed
EP-0542572-A1 Negative type radiation-sensitive resin composition JAPAN SYNTHETIC RUBBER CO., LTD. (JP) 1993-05-19 EP disclosed