Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 1/20 | 0.45 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.45 |
| ▸ | THRA | P10827 | 1/20 | 0.43 |
| ▸ | THRB | P10828 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | PPARD | Q03181 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | ADRB2 | P07550 | 2/20 | 0.37 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.37 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.37 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6930569 | 0.93 | THRA (0.46) | MTNR1AMTNR1BTHRATHRBCYP4F2 | |
| SCHEMBL6930576 | 0.86 | THRA (0.45) | MTNR1AMTNR1BTHRATHRBCYP4F2 | |
| SCHEMBL1836879 | 0.82 | THRA (0.57) | MTNR1AMTNR1BTHRATHRBHPGD | |
| SCHEMBL6555051 | 0.82 | CYP4F2 (0.37) | MTNR1AMTNR1BTHRATHRBCYP4F2 | |
| SCHEMBL1836159 | 0.80 | THRA (0.63) | MTNR1AMTNR1BTHRATHRBHPGD | |
| SCHEMBL1836108 | 0.79 | THRA (0.66) | THRATHRBHPGDKDM4EHSD17B10 | |
| SCHEMBL1841440 | 0.79 | THRA (0.66) | THRATHRBHPGDKDM4EHSD17B10 | |
| SCHEMBL1837530 | 0.79 | THRA (0.66) | THRATHRBHPGDKDM4EHSD17B10 | |
| SCHEMBL1835055 | 0.79 | THRA (0.66) | THRATHRBHPGDKDM4EHSD17B10 | |
| SCHEMBL1836935 | 0.79 | THRA (0.66) | THRATHRBHPGDKDM4EHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1214327-B1 | BLOCKED PHENYLALKYL SILANES | CROMPTON CORP (US) | 2004-02-25 | — | — | EP | claimed |