Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRA | P10827 | 1/20 | 0.46 |
| ▸ | THRB | P10828 | 1/20 | 0.46 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.41 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.41 |
| ▸ | CYP4F2 | P78329 | 2/20 | 0.40 |
| ▸ | CYP4A11 | Q02928 | 2/20 | 0.40 |
| ▸ | PTGS2 | P35354 | 3/20 | 0.38 |
| ▸ | PPARG | P37231 | 1/20 | 0.36 |
| ▸ | PPARA | Q07869 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6557117 | 0.93 | MTNR1A (0.45) | THRATHRBMTNR1AMTNR1BCYP4F2 | |
| SCHEMBL6930576 | 0.90 | THRA (0.45) | THRATHRBMTNR1AMTNR1BCYP4F2 | |
| SCHEMBL6555051 | 0.88 | CYP4F2 (0.37) | THRATHRBMTNR1AMTNR1BCYP4F2 | |
| SCHEMBL728259 | 0.80 | THRA (0.61) | THRATHRBMTNR1AMTNR1BPTGS2 | |
| SCHEMBL29416629 | 0.80 | THRA (0.61) | THRATHRBMTNR1AMTNR1BPTGS2 | |
| SCHEMBL29416690 | 0.79 | THRA (0.68) | THRATHRBPTGS2PPARGPPARA | |
| SCHEMBL244081 | 0.79 | THRA (0.68) | THRATHRBPTGS2PPARGPPARA | |
| SCHEMBL1835981 | 0.77 | THRA (0.71) | THRATHRBPTGS2PPARGPPARA | |
| SCHEMBL1838091 | 0.77 | THRA (0.71) | THRATHRBPTGS2PPARGPPARA | |
| SCHEMBL5168002 | 0.77 | THRA (0.71) | THRATHRBPTGS2PPARGPPARA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6559329-B2 | Deblocking of a trialkoxysilane compound acontaining carbonate or acetooxy group is done by hydrolysis or alcoholyis | CROMPTON CORPORATION | 2003-05-06 | — | — | US | claimed |
| US-6413646-B1 | Blocked phenolic silanes | CROMPTON CORPORATION | 2002-07-02 | — | — | US | claimed |
| EP-1214327-A1 | BLOCKED PHENOLIC SILANES | Crompton Corporation (US) | 2002-06-19 | — | — | EP | claimed |
| US-20020051890-A1 | Blocked phenolic silanes | WITCO CORPORATION | 2002-05-02 | — | — | US | claimed |
| WO-2001009145-A1 | BLOCKED PHENOLIC SILANES | CROMPTON CORPORATION (US) | 2001-02-08 | — | — | WO | claimed |
| US-6559329-B2 | Deblocking of a trialkoxysilane compound acontaining carbonate or acetooxy group is done by hydrolysis or alcoholyis | CROMPTON CORPORATION | 2003-05-06 | — | — | US | disclosed |
| US-6413646-B1 | Blocked phenolic silanes | CROMPTON CORPORATION | 2002-07-02 | — | — | US | disclosed |
| EP-1214327-A1 | BLOCKED PHENOLIC SILANES | Crompton Corporation (US) | 2002-06-19 | — | — | EP | disclosed |
| US-20020051890-A1 | Blocked phenolic silanes | WITCO CORPORATION | 2002-05-02 | — | — | US | disclosed |
| WO-2001009145-A1 | BLOCKED PHENOLIC SILANES | CROMPTON CORPORATION (US) | 2001-02-08 | — | — | WO | disclosed |