Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | HPGD | P15428 | 2/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.44 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.44 |
| ▸ | GAA | P10253 | 3/20 | 0.44 |
| ▸ | POLB | P06746 | 2/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | IDO1 | P14902 | 2/20 | 0.42 |
| ▸ | HTT | P42858 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | METAP2 | P50579 | 1/20 | 0.38 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17151505 | 0.79 | HCAR1 (0.50) | ALDH1A1HPGDHSD17B10POLBRAB9A | |
| SCHEMBL5906035 | 0.79 | HCAR1 (0.50) | ALDH1A1KDM4ERAB9ATDP1HTT | |
| SCHEMBL8721128 | 0.75 | HCAR1 (0.55) | ALDH1A1CYP1A2CYP2D6KDM4EPOLB | |
| SCHEMBL3518937 | 0.74 | HTT (0.62) | ALDH1A1HPGDHSD17B10CYP1A2KDM4E | |
| SCHEMBL6557227 | 0.72 | CRBN (0.56) | BRD4ALDH1A1HPGDHSD17B10CYP1A2 | |
| SCHEMBL7971125 | 0.68 | KDM4E (0.47) | BRD4ALDH1A1HPGDHSD17B10CYP1A2 | |
| SCHEMBL7805547 | 0.67 | CA12 (0.54) | BRD4ALDH1A1HPGDHSD17B10KDM4E | |
| SCHEMBL10790345 | 0.67 | BRD4 (0.56) | BRD4ALDH1A1KDM4EGAAPOLB | |
| SCHEMBL8544900 | 0.66 | POLB (0.65) | BRD4ALDH1A1HPGDHSD17B10CYP1A2 | |
| SCHEMBL8723259 | 0.66 | TDP1 (0.42) | RAB9ATDP1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050261330-A1 | Derivatives of 2,2,4-trisubstituted tetrahydrofuran an antifungal agents | RANBAXY LABORATORIES LIMITED (IN) | 2005-11-24 | — | — | US | disclosed |
| EP-1497298-A1 | DERIVATIVES OF 2,2,4-TRISUBSTITUTED TETRAHYDROFURAN AS ANTIFUNGAL AGENTS | RANBAXY LABORATORIES, LTD. (IN) | 2005-01-19 | — | — | EP | disclosed |
| WO-2003087106-A1 | DERIVATIVES OF 2,2,4-TRISUBSTITUTED TETRAHYDROFURAN AS ANTIFUNGAL AGENTS | RANBAXY LABORATORIES LIMITED (IN) | 2003-10-23 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050261330-A1 | Derivatives of 2,2,4-trisubstituted tetrahydrofuran an antifungal agents | ERG28, DPM1, CYP51A1 | BRD4 352/4885ALDH1A1 1062/4885HPGD 1636/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.