Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.52 |
| ▸ | TDO2 | P48775 | 1/20 | 0.44 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.42 |
| ▸ | PTGS2 | P35354 | 3/20 | 0.41 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.41 |
| ▸ | MAP4K4 | O95819 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | RELA | Q04206 | 5/20 | 0.40 |
| ▸ | NOS3 | P29474 | 1/20 | 0.40 |
| ▸ | CCNE2 | O96020 | 2/20 | 0.39 |
| ▸ | CCNE1 | P24864 | 2/20 | 0.39 |
| ▸ | CDK2 | P24941 | 2/20 | 0.39 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.39 |
| ▸ | IKBKB | O14920 | 1/20 | 0.38 |
| ▸ | CHUK | O15111 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3789841 | 0.91 | TAAR1 (0.50) | ALDH1A1TDO2KEAP1MEN1KMT2A | |
| SCHEMBL3950704 | 0.87 | ALDH1A1 (0.45) | ALDH1A1TDO2MAP4K4MEN1KMT2A | |
| SCHEMBL15269267 | 0.87 | ACHE (0.46) | ALDH1A1PTGS2PTGS1MEN1KMT2A | |
| SCHEMBL21087940 | 0.87 | ALDH1A1 (0.45) | ALDH1A1TDO2KEAP1MEN1KMT2A | |
| SCHEMBL3793169 | 0.86 | ALDH1A1 (0.54) | ALDH1A1KEAP1TAAR1CYP1A2CYP2C9 | |
| SCHEMBL29492484 | 0.86 | ALDH1A1 (0.54) | ALDH1A1KEAP1TAAR1CYP1A2CYP2C9 | |
| SCHEMBL1578302 | 0.86 | ALDH1A1 (0.43) | ALDH1A1TDO2PTGS2PTGS1MEN1 | |
| SCHEMBL29901139 | 0.85 | ALDH1A1 (0.62) | ALDH1A1KEAP1MEN1KMT2ATDP1 | |
| Hydrochloric Acid SCHEMBL9311952 | 0.85 | ALDH1A1 (0.52) | ALDH1A1KEAP1TAAR1CYP1A2CYP2C9 | |
| Ammonia Solution, Strong SCHEMBL11901716 | 0.85 | ALDH1A1 (0.52) | ALDH1A1KEAP1TAAR1CYP1A2CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20200308168-A1 | FLUOROPHENYL SUBSTITUTED MUSCARINIC RECEPTOR LIGANDS WITH SELECTIVITY FOR M3 OVER M2 | Friedrich-Alexander-Universität Erlangen-Nürnberg (DE) | 2020-10-01 | — | — | US | disclosed |
| US-20200308168-A1 | FLUOROPHENYL SUBSTITUTED MUSCARINIC RECEPTOR LIGANDS WITH SELECTIVITY FOR M3 OVER M2 | Friedrich-Alexander-Universität Erlangen-Nürnberg (DE) | 2020-10-01 | — | — | US | disclosed |
| WO-2019110521-A1 | FLUOROPHENYL SUBSTITUTED MUSCARINIC RECEPTOR LIGANDS WITH SELECTIVITY FOR M3 OVER M2 | Friedrich-Alexander-Universität Erlangen-Nürnberg (DE) | 2019-06-13 | — | — | WO | disclosed |
| EP-2683682-A1 | PROCESS FOR THE SYNTHESIS OF AMINOBIPHENYLENE | BASF SE (DE) | 2014-01-15 | — | — | EP | disclosed |
| EP-2546229-A1 | Method for synthesising aminobiphenyls | Friedrich-Alexander-Universität Erlangen-Nürnberg (DE) | 2013-01-16 | — | — | EP | disclosed |
| EP-2546229-A1 | Method for synthesising aminobiphenyls | Friedrich-Alexander-Universität Erlangen-Nürnberg (DE) | 2013-01-16 | — | — | EP | disclosed |
| WO-2012120003-A1 | PROCESS FOR THE SYNTHESIS OF AMINOBIPHENYLENE | Friedrich-Alexander-Universität Erlangen-Nürnberg (DE) | 2012-09-13 | — | — | WO | disclosed |
| WO-2012120003-A1 | PROCESS FOR THE SYNTHESIS OF AMINOBIPHENYLENE | Friedrich-Alexander-Universität Erlangen-Nürnberg (DE) | 2012-09-13 | — | — | WO | disclosed |
| EP-1003725-B1 | FLUOROPYRAZOLE-BIPHENYLAMIDE FUNGICIDES | BASF AG (DE) | 2004-12-29 | — | — | EP | disclosed |
| EP-0847388-B1 | HETEROCYCLICALLY SUBSTITUTED BIPHENYLAMIDE DERIVATIVES, THEIR PREPARATION AND THEIR USE AS FUNGICIDES | BASF AG (DE) | 2003-06-25 | — | — | EP | disclosed |
| EP-1003725-A1 | FLUOROPYRAZOLE-BIPHENYLAMIDE FUNGICIDES | BASF AKTIENGESELLSCHAFT (DE) | 2000-05-31 | — | — | EP | disclosed |
| US-5998450-A | FOR PLANTS | BASF AKTIENGESELLSCHAFT (DE) | 1999-12-07 | — | — | US | disclosed |
| WO-1999009013-A1 | FLUOROPYRAZOLE-BIPHENYLAMIDE FUNGICIDES | BASF AKTIENGESELLSCHAFT (DE) | 1999-02-25 | — | — | WO | disclosed |
| EP-0847388-A1 | HETEROCYCLICALLY SUBSTITUTED BIPHENYLAMIDE DERIVATIVES, THEIR PREPARATION AND THEIR USE AS FUNGICIDES | BASF AKTIENGESELLSCHAFT (DE) | 1998-06-17 | — | — | EP | disclosed |
| WO-1997008148-A1 | HETEROCYCLICALLY SUBSTITUTED BIPHENYLAMIDE DERIVATIVES, THEIR PREPARATION AND THEIR USE AS FUNGICIDES | BASF AKTIENGESELLSCHAFT (DE) | 1997-03-06 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200308168-A1 | FLUOROPHENYL SUBSTITUTED MUSCARINIC RECEPTOR LIGANDS WITH SELECTIVITY FOR M3 OVER M2 | CHRM2, CHRM3, CHRM5 | ALDH1A1 866/4885TDO2 987/4885KEAP1 2431/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.