Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.54 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.54 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.44 |
| ▸ | ADORA1 | P30542 | 3/20 | 0.42 |
| ▸ | ADORA2A | P29274 | 3/20 | 0.41 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.40 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.40 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | PTK2B | Q14289 | 1/20 | 0.40 |
| ▸ | METAP2 | P50579 | 1/20 | 0.40 |
| ▸ | SMARCA2 | P51531 | 1/20 | 0.39 |
| ▸ | SMARCA4 | P51532 | 1/20 | 0.39 |
| ▸ | PBRM1 | Q86U86 | 1/20 | 0.39 |
| ▸ | BACE1 | P56817 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29492484 | 1.00 | ALDH1A1 (0.54) | ALDH1A1HSD17B10KEAP1ADORA1ADORA2A | |
| Hydrochloric Acid SCHEMBL9311952 | 0.98 | ALDH1A1 (0.52) | ALDH1A1HSD17B10KEAP1ADORA1ADORA2A | |
| Ammonia Solution, Strong SCHEMBL11901716 | 0.98 | ALDH1A1 (0.52) | ALDH1A1HSD17B10KEAP1ADORA1ADORA2A | |
| SCHEMBL6557724 | 0.86 | ALDH1A1 (0.52) | ALDH1A1KEAP1TAAR1CYP1A2CYP2C9 | |
| SCHEMBL3789841 | 0.83 | TAAR1 (0.50) | ALDH1A1HSD17B10KEAP1TAAR1MAPT | |
| SCHEMBL3785218 | 0.83 | ALDH1A1 (0.54) | ALDH1A1HSD17B10KEAP1ADORA1ADORA2A | |
| SCHEMBL3783916 | 0.82 | MAOA (0.47) | ALDH1A1TAAR1MKNK1MKNK2MAPT | |
| SCHEMBL29901139 | 0.81 | ALDH1A1 (0.62) | ALDH1A1KEAP1CYP1A2BACE1HDAC1 | |
| SCHEMBL21088010 | 0.80 | ALDH1A1 (0.50) | ALDH1A1KEAP1TAAR1CYP1A2BACE1 | |
| SCHEMBL3787023 | 0.80 | ALDH1A1 (0.59) | ALDH1A1HSD17B10KEAP1ADORA2ACYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 28 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4688739-A1 | NOVEL PYRROLIDINIUM COMPOUNDS HAVING ANTAGONISTIC ACTIVITY AGAINST MUSCARINIC RECEPTORS AND USE THEREOF | eFlask Co., Ltd. (KR) | 2026-02-11 | — | — | EP | disclosed |
| WO-2024205157-A1 | NOVEL PYRROLIDINIUM COMPOUNDS HAVING ANTAGONISTIC ACTIVITY AGAINST MUSCARINIC RECEPTORS AND USE THEREOF | EFLASK CO., LTD. (KR) | 2024-10-03 | — | — | WO | disclosed |
| CN-112898352-B | Asymmetric palladium complex, preparation method and application thereof in catalyzing olefin polymerization | 中山大学 | 2022-03-22 | — | — | CN | disclosed |
| CN-112898352-A | Asymmetric palladium complex, preparation method and application thereof in catalyzing olefin polymerization | 中山大学 | 2021-06-04 | — | — | CN | disclosed |
| US-20200308168-A1 | FLUOROPHENYL SUBSTITUTED MUSCARINIC RECEPTOR LIGANDS WITH SELECTIVITY FOR M3 OVER M2 | Friedrich-Alexander-Universität Erlangen-Nürnberg (DE) | 2020-10-01 | — | — | US | disclosed |
| US-20200308168-A1 | FLUOROPHENYL SUBSTITUTED MUSCARINIC RECEPTOR LIGANDS WITH SELECTIVITY FOR M3 OVER M2 | Friedrich-Alexander-Universität Erlangen-Nürnberg (DE) | 2020-10-01 | — | — | US | disclosed |
| WO-2019110521-A1 | FLUOROPHENYL SUBSTITUTED MUSCARINIC RECEPTOR LIGANDS WITH SELECTIVITY FOR M3 OVER M2 | Friedrich-Alexander-Universität Erlangen-Nürnberg (DE) | 2019-06-13 | — | — | WO | disclosed |
| US-10246407-B2 | Process for preparing biphenylamines from anilides by ruthenium catalysis | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2019-04-02 | — | — | US | disclosed |
| US-10246408-B2 | Process for preparing biphenylamines from anilides by ruthenium catalysis | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2019-04-02 | — | — | US | disclosed |
| US-20170044094-A1 | PROCESS FOR PREPARING BIPHENYLAMINES FROM ANILIDES BY RUTHENIUM CATALYSIS | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2017-02-16 | — | — | US | disclosed |
| WO-2012120003-A1 | PROCESS FOR THE SYNTHESIS OF AMINOBIPHENYLENE | Friedrich-Alexander-Universität Erlangen-Nürnberg (DE) | 2012-09-13 | — | — | WO | disclosed |
| WO-2012120003-A1 | PROCESS FOR THE SYNTHESIS OF AMINOBIPHENYLENE | Friedrich-Alexander-Universität Erlangen-Nürnberg (DE) | 2012-09-13 | — | — | WO | disclosed |
| CN-101133016-B | Method for producing substituted biphenyls | BASF AG | 2010-06-02 | — | — | CN | disclosed |
| US-20100087680-A1 | METHOD FOR PRODUCING BIARYL COMPOUND | SUMITOMO CHEMICAL COMPANY LIMITED (JP) | 2010-04-08 | — | — | US | disclosed |
| EP-1914221-A1 | PROCESS FOR PRODUCING BIARYL COMPOUND | Sumitomo Chemical Company, Limited (JP) | 2008-04-23 | — | — | EP | disclosed |
| CN-101133016-A | Method for producing substituted biphenyls | BASF AG (DE) | 2008-02-27 | — | — | CN | disclosed |
| EP-0536151-B1 | ORTHOSUBSTITUTED BIPHENYL GUANIDINE DERIVATIVES AND ANTIDIABETIC OR HYPOGLYCAEMIC AGENTS CONTAINING THEM | BOOTS CO PLC (GB) | 1994-09-14 | — | — | EP | disclosed |
| US-5302720-A | Biphenyl-substituted guanidine derivatives useful as hypoglycaemic agents | THE BOOTS COMPANY (GB) | 1994-04-12 | — | — | US | disclosed |
| EP-0536151-A1 | ORTHOSUBSTITUTED BIPHENYL GUANIDINE DERIVATIVES AND ANTIDIABETIC OR HYPOGLYCAEMIC AGENTS CONTAINING THEM. | BOOTS CO PLC (GB) | 1993-04-14 | — | — | EP | disclosed |
| WO-1992000273-A1 | ORTHOSUBSTITUTED BIPHENYL AMIDINE AND BIPHENYL GUANIDINE DERIVATIVES AND ANTIDIABETIC OR HYPOGLYCAEMIC AGENTS CONTAINING THEM | THE BOOTS COMPANY PLC (GB) | 1992-01-09 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10246407-B2 | Process for preparing biphenylamines from anilides by ruthenium catalysis | SBDS, AGPS, CYP2B6 | ALDH1A1 392/4885HSD17B10 1351/4885KEAP1 1235/4885 |
| US-20100087680-A1 | METHOD FOR PRODUCING BIARYL COMPOUND | NISCH, BLVRB, BBOX1 | ALDH1A1 4339/4885HSD17B10 1100/4885KEAP1 1245/4885 |
| US-20200308168-A1 | FLUOROPHENYL SUBSTITUTED MUSCARINIC RECEPTOR LIGANDS WITH SELECTIVITY FOR M3 OVER M2 | CHRM2, CHRM3, CHRM5 | ALDH1A1 866/4885HSD17B10 3669/4885KEAP1 2431/4885 |
| US-10246408-B2 | Process for preparing biphenylamines from anilides by ruthenium catalysis | SBDS, AGPS, CYP2B6 | ALDH1A1 392/4885HSD17B10 1351/4885KEAP1 1235/4885 |
| US-20170044094-A1 | PROCESS FOR PREPARING BIPHENYLAMINES FROM ANILIDES BY RUTHENIUM CATALYSIS | SBDS, AGPS, CYP2B6 | ALDH1A1 392/4885HSD17B10 1351/4885KEAP1 1235/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.