SCHEMBL655820

SCHEMBL655820

Nc1ccc(OCC(=O)O)cc1

nearest known ligand 0.67

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALOX15 P16050 2/20 0.65
ALDH1A1 P00352 3/20 0.60
SMN1; SMN2 Q16637 2/20 0.58
FFAR1 O14842 1/20 0.58
PTPN7 P35236 2/20 0.56
MAPT P10636 2/20 0.56
MEN1 O00255 1/20 0.56
KMT2A Q03164 1/20 0.56
PTPN12 Q05209 1/20 0.56
TSHR P16473 3/20 0.53
NR4A1 P22736 1/20 0.53
APEX1 P27695 1/20 0.53
TDP1 Q9NUW8 1/20 0.50
PTGDR2 Q9Y5Y4 1/20 0.49
PPARG P37231 1/20 0.49
PPARD Q03181 1/20 0.49
HSD17B10 Q99714 1/20 0.49
MCL1 Q07820 1/20 0.49
GAA P10253 1/20 0.48
MAOA P21397 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL830710 0.98 ALOX15 (0.63) ALOX15ALDH1A1SMN1; SMN2FFAR1PTPN7
SCHEMBL38710 0.91 ALOX15 (0.55) ALOX15ALDH1A1SMN1; SMN2FFAR1PTPN7
SCHEMBL17154344 0.91 ALOX15 (0.55) ALOX15ALDH1A1SMN1; SMN2FFAR1PTPN7
SCHEMBL339492 0.89 ALOX15 (0.81) ALOX15ALDH1A1SMN1; SMN2FFAR1PTPN7
SCHEMBL17676526 0.84 TDP1 (0.52) ALOX15ALDH1A1SMN1; SMN2MAPTTSHR
SCHEMBL21418186 0.83 APP (0.53) ALOX15ALDH1A1SMN1; SMN2FFAR1TSHR
SCHEMBL3999558 0.83 TDP1 (0.51) ALDH1A1SMN1; SMN2MAPTMEN1KMT2A
4-Aminophenol SCHEMBL10751612 0.82 ALDH5A1 (0.47) ALOX15ALDH1A1SMN1; SMN2PTPN22
SCHEMBL14506351 0.82 ESR1 (0.47) ALOX15ALDH1A1SMN1; SMN2FFAR1PTPN7
SCHEMBL11552274 0.82 ALOX15 (0.71) ALOX15ALDH1A1SMN1; SMN2FFAR1PTPN7

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 311 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-11235874-A None JP disclosed
CN-116478113-A Method for detecting 4-chlorophenoxyacetic acid for non-diagnostic purpose 华南农业大学 2023-07-25 CN disclosed
WO-2022191865-A1 HAIR COLORANT ASSESSMENT, SELECTION AND FORMULATION SYSTEM Innovative Beauty LLC (US) 2022-09-15 WO disclosed
US-20220283032-A1 Hair Colorant Assessment, Selection And Formulation System Innovative Beauty LLC (US) 2022-09-08 US disclosed
CN-112575188-B Dialkyl amino phenoxyacetic acid extracting agent, preparation method and application thereof 福建省长汀金龙稀土有限公司 2022-08-19 CN disclosed
US-11378457-B1 Hair colorant assessment, selection and formulation system Innovative Beauty LLC (US) 2022-07-05 US disclosed
CN-114641473-A BRD9 bifunctional degradation agent and use method thereof 诺华股份有限公司 2022-06-17 CN disclosed
US-11137291-B1 Hair colorant assessment, selection and formulation system Innovative Beauty LLC (US) 2021-10-05 US disclosed
CN-109384663-B Synthesis method of 4-iodophenoxyacetic acid 国药集团化学试剂有限公司 2021-08-03 CN disclosed
US-11007193-B2 2,4-pyrimidinediamine compounds and their uses RIGEL PHARMACEUTICALS, INC. (US) 2021-05-18 US disclosed
EP-0211325-A2 Method of making heliographic and flexographic printing inks BAYER AG (DE) 1987-02-25 EP disclosed
US-4053626-A CHOLESTEROL LEVEL-LOWERING PHENOXYACETIC ACIDS MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DT) 1977-10-11 US disclosed
US-4051259-A ANOREXIGENIC AGENTS LES LABORATOIRES BRUNEAU & CIE (FR) 1977-09-27 US disclosed
US-4035144-A Dyeing preparations containing boric acid for preparing water-insoluble azo dyestuffs on fiber HOECHST AKTIENGESELLSCHAFT (DT) 1977-07-12 US disclosed
US-4032652-A SUBSTITUTED 2H-PYRAN-2,6(3H)-DIONE DERIVATIVES, PHARMACEUTICAL COMPOSITIONS COMPRISING SUCH DERIVATIVES AND METHODS OF INHIBITING THE ANTIGEN-ANTIBODY REACTION SMITHKLINE CORPORATION (US) 1977-06-28 US disclosed
US-4026896-A ANTIALLERGENS KISSEI YAKUHIN KOGYO KABUSHIKI KAISHA (KISSEI PHARMACEUTICAL CO. LTD.) (JA) 1977-05-31 US disclosed
US-3992386-A 4(Quinolyl)phenoxy alkanoic acid derivatives MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DT) 1976-11-16 US disclosed
US-3978080-A ANTIINFLAMMATORY, HYPOLIPIDEMIC CIBA-GEIGY CORPORATION (US) 1976-08-31 US disclosed
US-3960874-A ANTIINFLAMMATORY, HYPOLIPIDEMIC AGENTS CIBA-GEIGY CORPORATION (US) 1976-06-01 US disclosed
US-3957424-A Enzyme-activated oxidative process for coloring hair THE PROCTER & GAMBLE COMPANY (US) 1976-05-18 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11007193-B2 2,4-pyrimidinediamine compounds and their uses FCER2, FCGR1A, FCGR2A ALOX15 584/4885ALDH1A1 2891/4885SMN1; SMN2 4764/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.