Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BACE1 | P56817 | 5/20 | 0.37 |
| ▸ | CTSD | P07339 | 2/20 | 0.37 |
| ▸ | ECE1 | P42892 | 3/20 | 0.36 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.35 |
| ▸ | CASP3 | P42574 | 2/20 | 0.33 |
| ▸ | FURIN | P09958 | 1/20 | 0.33 |
| ▸ | PCSK6 | P29122 | 1/20 | 0.33 |
| ▸ | TASP1 | Q9H6P5 | 1/20 | 0.33 |
| ▸ | CASP2 | P42575 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6558747 | 0.89 | BACE1 (0.42) | BACE1CTSDECE1PSENEN | |
| SCHEMBL6558843 | 0.78 | BACE1 (0.38) | BACE1CTSDECE1PSENENFURIN | |
| SCHEMBL6558469 | 0.78 | — | — | |
| SCHEMBL6558875 | 0.78 | CASP1 (0.42) | BACE1CTSDPSENENCASP3CASP2 | |
| SCHEMBL6558450 | 0.77 | MAGI3 (0.37) | BACE1CTSDPSENENCASP3FURIN | |
| SCHEMBL22957956 | 0.77 | ECE1 (0.48) | BACE1CTSDECE1CASP3FURIN | |
| SCHEMBL6558456 | 0.77 | PSENEN (0.37) | BACE1PSENEN | |
| SCHEMBL6559672 | 0.76 | GNPAT (0.37) | BACE1CTSDECE1 | |
| SCHEMBL6558839 | 0.75 | PSENEN (0.36) | BACE1CTSDPSENENCASP3CASP2 | |
| SCHEMBL6558448 | 0.74 | PSENEN (0.39) | CTSDPSENENCASP3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0948523-B1 | PEPTIDOMIMETIC INHIBITORS OF THE HUMAN CYTOMEGALOVIRUS PROTEASE | BOEHRINGER INGELHEIM CA LTD (CA) | 2004-03-17 | — | — | EP | claimed |
| US-6291420-B1 | DETERGENT, | RHODIA CHIMIE (FR) | 2001-09-18 | — | — | US | disclosed |
| EP-0150894-B1 | FLEXIBLE CONTAINERS CONTAINING A LIQUID PRODUCT AND PREVENTION OF VACUUM COLLAPSE THEREIN | THE PROCTER & GAMBLE COMPANY (US) | 1988-05-18 | — | — | EP | disclosed |