Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAGI3 | Q5TCQ9 | 1/20 | 0.37 |
| ▸ | TASP1 | Q9H6P5 | 1/20 | 0.37 |
| ▸ | BACE1 | P56817 | 3/20 | 0.37 |
| ▸ | CTSD | P07339 | 1/20 | 0.37 |
| ▸ | FURIN | P09958 | 1/20 | 0.36 |
| ▸ | PCSK6 | P29122 | 1/20 | 0.36 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.36 |
| ▸ | BACE2 | Q9Y5Z0 | 1/20 | 0.34 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.34 |
| ▸ | PSMB2 | P49721 | 1/20 | 0.34 |
| ▸ | CASP1 | P29466 | 1/20 | 0.34 |
| ▸ | CASP3 | P42574 | 1/20 | 0.34 |
| ▸ | CASP4 | P49662 | 1/20 | 0.34 |
| ▸ | CASP5 | P51878 | 1/20 | 0.34 |
| ▸ | CASP9 | P55211 | 1/20 | 0.34 |
| ▸ | CASP6 | P55212 | 1/20 | 0.34 |
| ▸ | CASP8 | Q14790 | 1/20 | 0.34 |
| ▸ | CASP10 | Q92851 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6558747 | 0.88 | BACE1 (0.42) | BACE1CTSDPSENENCASP1 | |
| SCHEMBL6558811 | 0.85 | FURIN (0.46) | FURINPCSK6 | |
| SCHEMBL6558448 | 0.84 | PSENEN (0.39) | CTSDPSENENCASP1CASP3 | |
| SCHEMBL6559665 | 0.83 | PSENEN (0.43) | CTSDPSENENCASP1 | |
| SCHEMBL6559645 | 0.83 | ALDH1A1 (0.40) | CTSDFURINPCSK6PSENEN | |
| SCHEMBL6558875 | 0.81 | CASP1 (0.42) | BACE1CTSDPSENENCASP1CASP3 | |
| SCHEMBL6560709 | 0.80 | PSENEN (0.41) | CTSDPSENENCASP1 | |
| SCHEMBL6558465 | 0.80 | PSENEN (0.41) | CTSDPSENENCASP1 | |
| SCHEMBL6558839 | 0.79 | PSENEN (0.36) | BACE1CTSDPSENENCASP1CASP3 | |
| SCHEMBL6558510 | 0.78 | TASP1 (0.31) | TASP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0948523-B1 | PEPTIDOMIMETIC INHIBITORS OF THE HUMAN CYTOMEGALOVIRUS PROTEASE | BOEHRINGER INGELHEIM CA LTD (CA) | 2004-03-17 | — | — | EP | claimed |
| US-6291640-B1 | OLIGOPEPTIDES; SOLID PHASE SYNTHESIS | BOEHRINGER INGELHEIM LTD. (CA) | 2001-09-18 | — | — | US | claimed |
| EP-0948523-B1 | PEPTIDOMIMETIC INHIBITORS OF THE HUMAN CYTOMEGALOVIRUS PROTEASE | BOEHRINGER INGELHEIM CA LTD (CA) | 2004-03-17 | — | — | EP | disclosed |