Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PSMB1 | P20618 | 2/20 | 0.43 |
| ▸ | IL1RN | P18510 | 4/20 | 0.42 |
| ▸ | ERAP2 | Q6P179 | 4/20 | 0.42 |
| ▸ | ERAP1 | Q9NZ08 | 4/20 | 0.42 |
| ▸ | CTSS | P25774 | 3/20 | 0.42 |
| ▸ | CTSL | P07711 | 2/20 | 0.42 |
| ▸ | CTSK | P43235 | 1/20 | 0.42 |
| ▸ | PSMB11 | A5LHX3 | 1/20 | 0.40 |
| ▸ | PSMD11 | O00231 | 1/20 | 0.40 |
| ▸ | PSMD12 | O00232 | 1/20 | 0.40 |
| ▸ | PSMD14 | O00487 | 1/20 | 0.40 |
| ▸ | PSMA7 | O14818 | 1/20 | 0.40 |
| ▸ | PSMD3 | O43242 | 1/20 | 0.40 |
| ▸ | PSMC3 | P17980 | 1/20 | 0.40 |
| ▸ | PSMA1 | P25786 | 1/20 | 0.40 |
| ▸ | PSMA2 | P25787 | 1/20 | 0.40 |
| ▸ | PSMA3 | P25788 | 1/20 | 0.40 |
| ▸ | PSMA4 | P25789 | 1/20 | 0.40 |
| ▸ | PSMB8 | P28062 | 1/20 | 0.40 |
| ▸ | PSMB9 | P28065 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6560569 | 0.92 | METAP2 (0.40) | MMEMETAP2METAP1MMP9MMP14 | |
| SCHEMBL6560939 | 0.90 | METAP2 (0.41) | PSMB1IL1RNERAP2ERAP1BACE1 | |
| SCHEMBL6558570 | 0.89 | BACE1 (0.45) | BACE1BACE2METAP2METAP1CTSD | |
| SCHEMBL6559229 | 0.89 | METAP2 (0.45) | PSMB1IL1RNERAP2ERAP1MME | |
| SCHEMBL6560838 | 0.89 | CTSK (0.52) | PSMB1CTSSCTSLCTSKREN | |
| SCHEMBL6560842 | 0.87 | METAP2 (0.43) | PSMB1IL1RNERAP2ERAP1MME | |
| SCHEMBL6558918 | 0.87 | METAP2 (0.47) | PSMB1IL1RNERAP2ERAP1MME | |
| SCHEMBL6558906 | 0.87 | PSMB1 (0.43) | PSMB1BACE1BACE2METAP2METAP1 | |
| Hydrochloric Acid SCHEMBL6558938 | 0.87 | METAP2 (0.43) | PSMB1IL1RNERAP2ERAP1MME | |
| SCHEMBL6559351 | 0.86 | METAP2 (0.45) | PSMB1IL1RNERAP2ERAP1MME |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0998488-B1 | POLYOL-AMINO ACID COMPOUNDS HAVING ANTI-HELICOBACTER PYLORI ACTIVITY | TAKEDA CHEMICAL INDUSTRIES LTD (JP) | 2004-03-17 | — | — | EP | disclosed |
| US-6423869-B1 | BACTERICIDES, ANTIULCER AGENTS | TAKEDA CHEMICAL INDUSTRIES, INC. (JP) | 2002-07-23 | — | — | US | disclosed |