SCHEMBL6558629

SCHEMBL6558629

CCOC(=O)COc1cc(Cl)c(Cl)cc1Cl

nearest known ligand 0.70

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 1/20 0.70
L3MBTL1 Q9Y468 4/20 0.69
TDP1 Q9NUW8 2/20 0.69
TSHR P16473 1/20 0.69
GAA P10253 2/20 0.60
PKM P14618 1/20 0.60
PPOX P50336 1/20 0.54
ALDH1A1 P00352 3/20 0.51
KMT2A Q03164 3/20 0.48
MEN1 O00255 2/20 0.48
NPSR1 Q6W5P4 2/20 0.48
MAPT P10636 1/20 0.48
KDM4E B2RXH2 1/20 0.48
HPGD P15428 1/20 0.48
CASP1 P29466 1/20 0.48
HSD17B10 Q99714 1/20 0.48
NPC1 O15118 1/20 0.47
RAB9A P51151 1/20 0.47
SMN1; SMN2 Q16637 1/20 0.47
FKBP1A P62942 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2789871 0.87 GAA (0.55) LMNAL3MBTL1TDP1TSHRGAA
SCHEMBL15040809 0.85 GAA (0.53) LMNAL3MBTL1TDP1TSHRGAA
SCHEMBL13247758 0.85 TSHR (0.54) LMNAL3MBTL1TDP1TSHRGAA
SCHEMBL13247345 0.85 L3MBTL1 (0.52) LMNAL3MBTL1TDP1TSHRGAA
SCHEMBL29827665 0.84 ALDH1A1 (0.72) LMNAL3MBTL1TDP1TSHRGAA
SCHEMBL4159382 0.84 ALDH1A1 (0.72) LMNAL3MBTL1TDP1TSHRGAA
SCHEMBL29702746 0.83 ALDH1A1 (0.67) LMNAL3MBTL1TDP1TSHRGAA
SCHEMBL11803571 0.83 ALDH1A1 (0.67) LMNAL3MBTL1TDP1TSHRGAA
SCHEMBL6812681 0.82 L3MBTL1 (0.50) LMNAL3MBTL1TDP1TSHRGAA
SCHEMBL6809927 0.82 L3MBTL1 (0.50) LMNAL3MBTL1TDP1TSHRGAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0957684-B1 MICROEMULSION AND METHOD TROY TECHNOLOGY CORP INC (US) 2004-03-17 EP claimed
EP-0957684-B1 MICROEMULSION AND METHOD TROY TECHNOLOGY CORP INC (US) 2004-03-17 EP disclosed
US-4642349-A REACTING AROMATIC CARBONATE AND ORGANIC HALIDE THE DOW CHEMICAL COMPANY (US) 1987-02-10 US disclosed