SCHEMBL4159382

SCHEMBL4159382

CCCCOC(=O)COc1cc(Cl)c(Cl)cc1Cl

nearest known ligand 0.72

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.72
L3MBTL1 Q9Y468 3/20 0.72
TDP1 Q9NUW8 2/20 0.72
TSHR P16473 2/20 0.62
LMNA P02545 2/20 0.62
PKM P14618 2/20 0.52
GAA P10253 1/20 0.52
MAPK1 P28482 1/20 0.49
NPSR1 Q6W5P4 1/20 0.49
ESR1 P03372 1/20 0.47
KDM4E B2RXH2 1/20 0.46
HSD17B10 Q99714 1/20 0.46
PPOX P50336 1/20 0.45
MAPT P10636 1/20 0.44
NPC1 O15118 2/20 0.44
RAB9A P51151 2/20 0.44
SMN1; SMN2 Q16637 2/20 0.44
KMT2A Q03164 2/20 0.44
CYP1A2 P05177 1/20 0.44
CYP2C9 P11712 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29827665 1.00 ALDH1A1 (0.72) ALDH1A1L3MBTL1TDP1TSHRLMNA
SCHEMBL29702746 0.95 ALDH1A1 (0.67) ALDH1A1L3MBTL1TDP1TSHRLMNA
SCHEMBL11803571 0.95 ALDH1A1 (0.67) ALDH1A1L3MBTL1TDP1TSHRLMNA
SCHEMBL5933296 0.94 ALDH1A1 (0.66) ALDH1A1L3MBTL1TDP1TSHRLMNA
SCHEMBL31349917 0.93 ALDH1A1 (0.64) ALDH1A1L3MBTL1TDP1TSHRLMNA
SCHEMBL5933755 0.92 ALDH1A1 (0.62) ALDH1A1L3MBTL1TDP1TSHRLMNA
SCHEMBL31650885 0.91 TDP1 (0.90) ALDH1A1L3MBTL1TDP1TSHRLMNA
SCHEMBL29460353 0.86 TDP1 (0.72) ALDH1A1L3MBTL1TDP1TSHRLMNA
SCHEMBL29558700 0.84 TDP1 (1.00) ALDH1A1L3MBTL1TDP1TSHRPKM
SCHEMBL1226040 0.84 TDP1 (1.00) ALDH1A1L3MBTL1TDP1TSHRPKM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12325646-B2 Fertigation water treatment UNIVERSITY OF GUELPH (CA) 2025-06-10 US disclosed
US-20250024837-A1 PESTICIDE SYSTEM BANISH, MICHELE 2025-01-23 US disclosed
US-20220234916-A1 WATER TREATMENT UNIVERSITY OF GUELPH (CA) 2022-07-28 US disclosed
US-20090064857-A1 Pump Plungers and Methods COORSTEK, INC. (US) 2009-03-12 US disclosed
US-20060276339-A1 Methods and compositions for increasing the efficacy of biologically-active ingredients BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM 2006-12-07 US disclosed
US-7134851-B2 Reciprocating pump having a ceramic piston COORSTEK, INC. (US) 2006-11-14 US disclosed
US-20050031466-A1 Pump plungers and methods COORSTEK, INC. (US) 2005-02-10 US disclosed
US-20040213690-A1 Pump with ceramic seal and methods for producing COORSTEK, INC. 2004-10-28 US disclosed
EP-0021294-B1 CHEMICAL DETOXIFICATION OF TOXIC CHLORINATED AROMATIC COMPOUNDS Vertac Chemical Corporation (US) 1984-10-10 EP disclosed
US-4327027-A Chemical detoxification of toxic chlorinated aromatic compounds VERTAC CHEMICAL CORPORATION (US) 1982-04-27 US disclosed
EP-0021294-A1 Chemical detoxification of toxic chlorinated aromatic compounds Vertac Chemical Corporation (US) 1981-01-07 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20060276339-A1 Methods and compositions for increasing the efficacy of biologically-active ingredients ENPP1, ENPP3, SMPD1 ALDH1A1 2504/4885L3MBTL1 3588/4885TDP1 696/4885
US-20250024837-A1 PESTICIDE SYSTEM ACHE, PFAS, FPGS ALDH1A1 3501/4885L3MBTL1 4185/4885TDP1 100/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.