Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.60 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.60 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.60 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.60 |
| ▸ | TSHR | P16473 | 1/20 | 0.60 |
| ▸ | PHLPP2 | Q6ZVD8 | 1/20 | 0.60 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.60 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.60 |
| ▸ | VCAM1 | P19320 | 13/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.41 |
| ▸ | GRM8 | O00222 | 1/20 | 0.41 |
| ▸ | GRM6 | O15303 | 1/20 | 0.41 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7973695 | 0.82 | MAPT (0.61) | MAPTMAPK1VCAM1ALDH1A1MEN1 | |
| Hydrochloric Acid SCHEMBL30729425 | 0.81 | MAPT (0.59) | MAPTMAPK1VCAM1ALDH1A1MEN1 | |
| SCHEMBL6556764 | 0.78 | MAPT (0.68) | MAPTMAPK1CYP1A2CYP3A4TSHR | |
| SCHEMBL30054040 | 0.78 | MAPT (0.68) | MAPTMAPK1CYP1A2CYP3A4TSHR | |
| SCHEMBL6558956 | 0.77 | MAPT (0.54) | MAPTMAPK1CYP1A2CYP3A4TSHR | |
| SCHEMBL7542108 | 0.77 | VCAM1 (0.64) | VCAM1ALDH1A1 | |
| SCHEMBL9886771 | 0.76 | VCAM1 (0.55) | MAPTMAPK1CYP1A2CYP3A4TDP1 | |
| SCHEMBL6558976 | 0.76 | MAPT (1.00) | MAPTMAPK1CYP1A2CYP3A4TSHR | |
| SCHEMBL6556773 | 0.75 | MAPT (0.62) | MAPTMAPK1CYP1A2CYP3A4TSHR | |
| SCHEMBL6556688 | 0.75 | MAPT (0.71) | MAPTMAPK1CYP1A2CYP3A4TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1100483-B1 | GLUCOCORTICOID-SELECTIVE ANTI-INFLAMMATORY AGENTS | ABBOTT LAB (US) | 2004-09-29 | — | — | EP | claimed |
| US-6166013-A | Glucocortiocoid-selective agents | ABBOTT LABORATORIES (US) | 2000-12-26 | — | — | US | disclosed |