Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 7/20 | 0.55 |
| ▸ | MAOB | P27338 | 7/20 | 0.55 |
| ▸ | NPC1 | O15118 | 3/20 | 0.50 |
| ▸ | RAB9A | P51151 | 3/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
| ▸ | SRC | P12931 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | CCNB2 | O95067 | 1/20 | 0.42 |
| ▸ | CDK1 | P06493 | 1/20 | 0.42 |
| ▸ | CDK4 | P11802 | 1/20 | 0.42 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.42 |
| ▸ | CCND1 | P24385 | 1/20 | 0.42 |
| ▸ | CCNB3 | Q8WWL7 | 1/20 | 0.42 |
| ▸ | MAP1LC3B | Q9GZQ8 | 1/20 | 0.42 |
| ▸ | MAP1LC3A | Q9H492 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29549500 | 0.92 | MAOA (0.58) | MAOAMAOBNPC1RAB9ATDP1 | |
| SCHEMBL429910 | 0.92 | MAOA (0.58) | MAOAMAOBNPC1RAB9ATDP1 | |
| 3-(Allyloxy)Phenol SCHEMBL27494286 | 0.85 | APP (0.47) | NPC1RAB9AMEN1KMT2AMAP1LC3B | |
| 3-(Allyloxy)Phenol SCHEMBL483058 | 0.85 | APP (0.50) | NPC1RAB9AMEN1KMT2AMAP1LC3B | |
| 3-(Allyloxy)Phenol SCHEMBL27721429 | 0.84 | APP (0.49) | NPC1RAB9AMEN1KMT2AMAP1LC3B | |
| 3-(Allyloxy)Phenol SCHEMBL6308372 | 0.82 | KAT6A (0.43) | NPC1RAB9AMEN1KMT2AMAP1LC3B | |
| 3-(Allyloxy)Phenol SCHEMBL27494285 | 0.81 | KAT6A (0.47) | NPC1RAB9AMAP1LC3BMAP1LC3A | |
| SCHEMBL8671875 | 0.81 | KDM4E (0.44) | MAOAMAOBNPC1RAB9AMEN1 | |
| 3-(Allyloxy)Phenol SCHEMBL6690965 | 0.81 | CHRNB2 (0.46) | NPC1RAB9AMEN1KMT2AMAP1LC3B | |
| 3-(Allyloxy)Phenol SCHEMBL27650695 | 0.81 | DRD2 (0.48) | NPC1RAB9AMEN1KMT2AMAP1LC3B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1392643-A2 | TRISUBSTITUTED-N- (1S)-1,2,3,4-TETRAHYDRO-1-NAPHTHALENYL] BENZAMIDES WHICH INHIBIT P2X3 AND P2X2/3 CONTAINING RECEPTORS | Abbott Laboratories (US) | 2004-03-03 | — | — | EP | disclosed |
| WO-2002094767-A2 | TRISUBSTITUTED-N-[(1S)-1,2,3,4-TETRAHYDRO-1-NAPHTHALENYL] BENZAMIDES WHICH INHIBIT P2X3 AND P2X2/3 CONTAINING RECEPTORS | ABBOTT LABORATORIES (US) | 2002-11-28 | — | — | WO | disclosed |