Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | METAP2 | P50579 | 3/20 | 0.40 |
| ▸ | METAP1 | P53582 | 3/20 | 0.40 |
| ▸ | CYP26A1 | O43174 | 3/20 | 0.39 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.38 |
| ▸ | KEAP1 | Q14145 | 2/20 | 0.37 |
| ▸ | NFE2L2 | Q16236 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | CTSA | P10619 | 4/20 | 0.35 |
| ▸ | GPR88 | Q9GZN0 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6559733 | 0.92 | METAP2 (0.48) | METAP2METAP1SCN9AALDH1A1LMNA | |
| Hydrochloric Acid SCHEMBL6559799 | 0.91 | METAP2 (0.47) | METAP2METAP1SCN9AALDH1A1LMNA | |
| SCHEMBL6560489 | 0.85 | METAP2 (0.47) | METAP2METAP1SCN9AALDH1A1LMNA | |
| SCHEMBL6559229 | 0.83 | METAP2 (0.45) | METAP2METAP1SCN9A | |
| SCHEMBL6558906 | 0.83 | PSMB1 (0.43) | METAP2METAP1SCN9A | |
| Hydrochloric Acid SCHEMBL6560650 | 0.82 | METAP2 (0.45) | METAP2METAP1SCN9AALDH1A1LMNA | |
| SCHEMBL6560842 | 0.82 | METAP2 (0.43) | METAP2METAP1SCN9A | |
| SCHEMBL6559295 | 0.82 | METAP2 (0.47) | METAP2METAP1CYP26A1CTSAGPR88 | |
| SCHEMBL6560871 | 0.82 | METAP2 (0.45) | METAP2METAP1SCN9AALDH1A1LMNA | |
| SCHEMBL6559201 | 0.81 | METAP2 (0.47) | METAP2METAP1KDM4EALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0998488-B1 | POLYOL-AMINO ACID COMPOUNDS HAVING ANTI-HELICOBACTER PYLORI ACTIVITY | TAKEDA CHEMICAL INDUSTRIES LTD (JP) | 2004-03-17 | — | — | EP | disclosed |
| US-6423869-B1 | BACTERICIDES, ANTIULCER AGENTS | TAKEDA CHEMICAL INDUSTRIES, INC. (JP) | 2002-07-23 | — | — | US | disclosed |