Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.62 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.62 |
| ▸ | TPMT | P51580 | 1/20 | 0.56 |
| ▸ | MAPT | P10636 | 4/20 | 0.53 |
| ▸ | POLB | P06746 | 4/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | CA12 | O43570 | 1/20 | 0.50 |
| ▸ | CA1 | P00915 | 1/20 | 0.50 |
| ▸ | CA2 | P00918 | 1/20 | 0.50 |
| ▸ | CA3 | P07451 | 1/20 | 0.50 |
| ▸ | PKM | P14618 | 1/20 | 0.50 |
| ▸ | CA4 | P22748 | 1/20 | 0.50 |
| ▸ | CA6 | P23280 | 1/20 | 0.50 |
| ▸ | CA5A | P35218 | 1/20 | 0.50 |
| ▸ | CA7 | P43166 | 1/20 | 0.50 |
| ▸ | CA9 | Q16790 | 1/20 | 0.50 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.50 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| 3,4,5-Trimethoxybenzoic Acid SCHEMBL6559147 | 0.85 | TPMT (0.71) | TPMTMAPTPOLBCA12CA1 | |
| SCHEMBL618766 | 0.83 | CA12 (0.61) | MEN1KMT2AMAPTPOLBALDH1A1 | |
| SCHEMBL9970898 | 0.83 | MEN1 (0.81) | MEN1KMT2ATPMTMAPTPOLB | |
| 3,4,5-Trimethoxybenzoic Acid SCHEMBL6592 | 0.79 | TPMT (0.78) | KMT2ATPMTMAPTALDH1A1CA12 | |
| SCHEMBL13266325 | 0.79 | MEN1 (0.74) | MEN1KMT2AMAPTPOLBALDH1A1 | |
| SCHEMBL13064968 | 0.78 | MAPT (0.74) | MEN1KMT2AMAPTPOLBALDH1A1 | |
| SCHEMBL21465837 | 0.78 | CA12 (0.58) | MEN1KMT2AMAPTPOLBALDH1A1 | |
| 3,4,5-Trimethoxybenzoic Acid SCHEMBL10838612 | 0.78 | TPMT (0.75) | KMT2ATPMTMAPTALDH1A1CA12 | |
| 3,4,5-Trimethoxybenzoic Acid SCHEMBL11023602 | 0.78 | TPMT (0.75) | KMT2ATPMTMAPTALDH1A1CA12 | |
| 3,4,5-Trimethoxybenzoic Acid SCHEMBL9739818 | 0.78 | TPMT (0.75) | KMT2ATPMTMAPTALDH1A1CA12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9052324-B2 | Compounds and assays for controlling Wnt activity | ENZO BIOCHEM, INC. (US) | 2015-06-09 | — | — | US | disclosed |
| US-20120322717-A9 | Compounds and assays for controlling Wnt activity | ENZO BIOCHEM, INC. | 2012-12-20 | — | — | US | disclosed |
| US-20100298200-A1 | Compounds and assays for controlling Wnt activity | LIU DAKAI | 2010-11-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120322717-A9 | Compounds and assays for controlling Wnt activity | WNT1, WNT3A, WNT3 | MEN1 3364/4885KMT2A 4381/4885TPMT 3617/4885 |
| US-20100298200-A1 | Compounds and assays for controlling Wnt activity | WNT1, WNT3A, WNT3 | MEN1 3364/4885KMT2A 4381/4885TPMT 3617/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.