Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSD | P07339 | 11/20 | 0.43 |
| ▸ | METAP2 | P50579 | 3/20 | 0.42 |
| ▸ | METAP1 | P53582 | 3/20 | 0.42 |
| ▸ | BACE1 | P56817 | 1/20 | 0.37 |
| ▸ | MMP9 | P14780 | 1/20 | 0.37 |
| ▸ | MMP8 | P22894 | 1/20 | 0.37 |
| ▸ | MMP14 | P50281 | 1/20 | 0.37 |
| ▸ | PSMB1 | P20618 | 1/20 | 0.37 |
| ▸ | GPR88 | Q9GZN0 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6559308 | 1.00 | CTSD (0.43) | CTSDMETAP2METAP1BACE1MMP9 | |
| SCHEMBL7787138 | 0.94 | METAP2 (0.43) | CTSDMETAP2METAP1GPR88 | |
| SCHEMBL6559811 | 0.93 | METAP2 (0.47) | METAP2METAP1GPR88 | |
| SCHEMBL6559807 | 0.93 | METAP2 (0.47) | METAP2METAP1GPR88 | |
| SCHEMBL29711383 | 0.92 | METAP2 (0.44) | CTSDMETAP2METAP1BACE1MMP9 | |
| SCHEMBL6559357 | 0.92 | METAP2 (0.44) | CTSDMETAP2METAP1BACE1MMP9 | |
| SCHEMBL6560488 | 0.92 | METAP2 (0.44) | CTSDMETAP2METAP1BACE1MMP9 | |
| SCHEMBL6558968 | 0.92 | CTSD (0.50) | CTSD | |
| SCHEMBL6558962 | 0.92 | CTSD (0.50) | CTSD | |
| SCHEMBL7784103 | 0.91 | METAP2 (0.42) | CTSDMETAP2METAP1BACE1GPR88 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0998488-B1 | POLYOL-AMINO ACID COMPOUNDS HAVING ANTI-HELICOBACTER PYLORI ACTIVITY | TAKEDA CHEMICAL INDUSTRIES LTD (JP) | 2004-03-17 | — | — | EP | claimed |
| US-6423869-B1 | BACTERICIDES, ANTIULCER AGENTS | TAKEDA CHEMICAL INDUSTRIES, INC. (JP) | 2002-07-23 | — | — | US | claimed |
| EP-0998488-B1 | POLYOL-AMINO ACID COMPOUNDS HAVING ANTI-HELICOBACTER PYLORI ACTIVITY | TAKEDA CHEMICAL INDUSTRIES LTD (JP) | 2004-03-17 | — | — | EP | disclosed |
| US-6423869-B1 | BACTERICIDES, ANTIULCER AGENTS | TAKEDA CHEMICAL INDUSTRIES, INC. (JP) | 2002-07-23 | — | — | US | disclosed |