Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | METAP2 | P50579 | 3/20 | 0.42 |
| ▸ | METAP1 | P53582 | 3/20 | 0.42 |
| ▸ | BACE1 | P56817 | 6/20 | 0.38 |
| ▸ | GPR88 | Q9GZN0 | 4/20 | 0.37 |
| ▸ | CTSD | P07339 | 2/20 | 0.35 |
| ▸ | CASP1 | P29466 | 1/20 | 0.34 |
| ▸ | CASP3 | P42574 | 1/20 | 0.34 |
| ▸ | CASP7 | P55210 | 1/20 | 0.34 |
| ▸ | CASP8 | Q14790 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7784098 | 1.00 | METAP2 (0.42) | METAP2METAP1BACE1GPR88CTSD | |
| SCHEMBL7787138 | 0.94 | METAP2 (0.43) | METAP2METAP1GPR88CTSD | |
| SCHEMBL6559807 | 0.93 | METAP2 (0.47) | METAP2METAP1GPR88 | |
| SCHEMBL6559811 | 0.93 | METAP2 (0.47) | METAP2METAP1GPR88 | |
| SCHEMBL6559302 | 0.91 | CTSD (0.43) | METAP2METAP1BACE1GPR88CTSD | |
| SCHEMBL6559308 | 0.91 | CTSD (0.43) | METAP2METAP1BACE1GPR88CTSD | |
| SCHEMBL6559210 | 0.89 | METAP2 (0.40) | METAP2METAP1GPR88CTSDCASP1 | |
| SCHEMBL6559216 | 0.89 | METAP2 (0.40) | METAP2METAP1GPR88CTSDCASP1 | |
| SCHEMBL7787115 | 0.87 | METAP2 (0.44) | METAP2METAP1BACE1GPR88CTSD | |
| SCHEMBL6559251 | 0.84 | METAP2 (0.49) | METAP2METAP1GPR88 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1140979-A1 | POLYOL COMPOUNDS, THEIR PRODUCTION AND USE | Takeda Chemical Industries, Ltd. (JP) | 2001-10-10 | — | — | EP | disclosed |
| WO-2000040599-A1 | POLYOL COMPOUNDS, THEIR PRODUCTION AND USE | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 2000-07-13 | — | — | WO | disclosed |