Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.61 |
| ▸ | KDM4E | B2RXH2 | 13/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 12/20 | 0.53 |
| ▸ | GAA | P10253 | 8/20 | 0.53 |
| ▸ | HPGD | P15428 | 6/20 | 0.53 |
| ▸ | GLA | P06280 | 5/20 | 0.53 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.53 |
| ▸ | CASP1 | P29466 | 2/20 | 0.53 |
| ▸ | CASP7 | P55210 | 1/20 | 0.53 |
| ▸ | MAOB | P27338 | 2/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | CTSD | P07339 | 1/20 | 0.44 |
| ▸ | BACE1 | P56817 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | PGR | P06401 | 2/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | CNR1 | P21554 | 1/20 | 0.42 |
| ▸ | CNR2 | P34972 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6559273 | 0.87 | MAPT (0.60) | MAPTKDM4EALDH1A1GAAHPGD | |
| SCHEMBL7029616 | 0.79 | HTR2B (0.43) | MAPTKDM4EALDH1A1HPGDMAOB | |
| SCHEMBL30065841 | 0.79 | ALDH1A1 (0.60) | MAPTKDM4EALDH1A1GAAHPGD | |
| SCHEMBL544297 | 0.79 | ALDH1A1 (0.60) | MAPTKDM4EALDH1A1GAAHPGD | |
| SCHEMBL6561022 | 0.78 | BCL2L1 (0.43) | MAPTKDM4EALDH1A1GAAHPGD | |
| SCHEMBL6561017 | 0.78 | BCL2L1 (0.43) | MAPTKDM4EALDH1A1GAAHPGD | |
| SCHEMBL68892 | 0.78 | MAPT (0.69) | MAPTKDM4EALDH1A1GAAHPGD | |
| SCHEMBL2431654 | 0.78 | CTSD (0.41) | MAPTKDM4EGAAMAOBMEN1 | |
| SCHEMBL3012963 | 0.77 | BCL2L1 (0.60) | MAPTKDM4EALDH1A1GAAHPGD | |
| SCHEMBL3353464 | 0.77 | MAPT (0.68) | MAPTKDM4EALDH1A1GAAHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0807629-B1 | Sulfonamido substituted chromane derivatives, method for their preparation, their use as medicaments or diagnostic agents aswell as medicaments containing them | AVENTIS PHARMA GMBH (DE) | 2004-03-03 | — | — | EP | disclosed |
| US-6191164-B1 | POTASSIUM CHANNEL MODULATORS; ANTIULCER AGENTS | HOECHST AKTIENGESELLSCHAFT (DE) | 2001-02-20 | — | — | US | disclosed |
| EP-0807629-A1 | Sulfonamido substituted chromane derivatives, method for their preparation, their use as medicaments or diagnostic agents aswell as medicaments containing them | HOECHST AKTIENGESELLSCHAFT (DE) | 1997-11-19 | — | — | EP | disclosed |