Hydrochloric Acid

Hydrochloric Acid

SCHEMBL6559595

C[Si](C)(C1c2ccccc2-c2ccccc21)C1c2ccccc2-c2ccccc21.[Cl-].[Cl-].[Zr+2]

nearest known ligand 0.43

Full drug profile on Sugi Atlas →

Known targets — ChEMBL curated mechanism

ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA

The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ACHE known ✓ P22303 2/20 0.35
CHRM2 known ✓ P08172 1/20 0.35
CHRM1 known ✓ P11229 1/20 0.35
SLC6A2 known ✓ P23975 1/20 0.35
SLC6A3 known ✓ Q01959 1/20 0.35
GPR3 P46089 2/20 0.43
CYP19A1 P11511 1/20 0.38
HTR2A P28223 1/20 0.38
POLB P06746 2/20 0.36
HTR1A P08908 1/20 0.35
ADRA2A P08913 1/20 0.35
DRD1 P21728 1/20 0.35
SLC6A4 P31645 1/20 0.35
ADRA1A P35348 1/20 0.35
OPRM1 P35372 1/20 0.35
DRD3 P35462 1/20 0.35
HRH3 Q9Y5N1 1/20 0.35
KMT2A Q03164 2/20 0.34
SLC22A2 O15244 1/20 0.34
SLC22A3 O75751 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5175634 0.95 GPR3 (0.46) GPR3CYP19A1HTR2APOLBACHE
Hydrochloric Acid SCHEMBL6559588 0.91 GPR3 (0.43) GPR3CYP19A1HTR2APOLBACHE
SCHEMBL7946417 0.81 GPR3 (0.36) GPR3CYP19A1HTR2APOLBACHE
SCHEMBL30390148 0.80 GPR3 (0.46) GPR3CYP19A1HTR2APOLBACHE
SCHEMBL6671925 0.80 GPR3 (0.46) GPR3CYP19A1HTR2APOLBACHE
SCHEMBL5981387 0.80 GPR3 (0.46) GPR3CYP19A1HTR2APOLBACHE
SCHEMBL30885513 0.79 GPR3 (0.38) GPR3CYP19A1HTR2APOLBACHE
Hydrochloric Acid SCHEMBL8534599 0.78 GPR3 (0.32) GPR3HTR2ACHRM2CHRM1SLC6A2
SCHEMBL1452791 0.78 SLC6A2 (0.43) GPR3HTR2AADRA2ADRD1SLC6A2
Hydrochloric Acid SCHEMBL6295840 0.77 GPR3 (0.36) GPR3CYP19A1HTR2APOLBACHE

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0753529-B1 Cross-linked atactic or amorphous propylene polymers BASELL POLYOLEFINE GMBH (DE) 2004-04-07 EP disclosed
EP-1021485-B1 PARTIALLY CROSS-LINKED ELASTOMERIC POLYOLEFIN MIXTURES BASELL POLIOLEFINE SPA (IT) 2004-03-24 EP disclosed
US-6448335-B1 IONOMERIC MIXTURES OF OLEFIN POLYMERS FUNCTIONALIZED WITH FULLY OR PARTIALLY METAL NEUTRALIZED CARBOXYLIC ACIDS; ABRASION RESISTANCE; TACTILE, I.E. SOFT, SMOOTH, SATINY TEXTURE; SYNTHETIC LEATHER; SUBSTITUTE FOR POLYVINYLCHLORIDE BASELL POLIOLEFINE ITALIA S.P.A. (IT) 2002-09-10 US disclosed
EP-1021485-A1 PARTIALLY CROSS-LINKED ELASTOMERIC POLYOLEFIN MIXTURES Montell North America Inc. (US) 2000-07-26 EP disclosed
WO-1999015584-A1 PARTIALLY CROSS-LINKED ELASTOMERIC POLYOLEFIN MIXTURES MONTELL NORTH AMERICA INC. (US) 1999-04-01 WO disclosed
US-5840109-A MIXTURE OF BITUMEN WITH PROPYLENE POLYMER OR COPOLYMER MONTELL NORTH AMERICA INC. (US) 1998-11-24 US disclosed
US-5712323-A Cross -linked atactic or amorphous propylene polymers MONTELL NORTH AMERICA INC. (US) 1998-01-27 US disclosed
EP-0753529-A2 Cross-linked atactic or amorphous propylene polymers MONTELL NORTH AMERICA INC. (US) 1997-01-15 EP disclosed