SCHEMBL7946417

SCHEMBL7946417

CC1=C(C)C([Si](C)(C)C2c3ccccc3-c3ccccc32)c2ccccc21

nearest known ligand 0.36

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GPR3 P46089 2/20 0.36
HTR2A P28223 1/20 0.32
POLB P06746 2/20 0.32
ACHE P22303 2/20 0.31
CHRM2 P08172 1/20 0.31
HTR1A P08908 1/20 0.31
ADRA2A P08913 1/20 0.31
CHRM1 P11229 1/20 0.31
DRD1 P21728 1/20 0.31
SLC6A2 P23975 1/20 0.31
SLC6A4 P31645 1/20 0.31
ADRA1A P35348 1/20 0.31
OPRM1 P35372 1/20 0.31
DRD3 P35462 1/20 0.31
SLC6A3 Q01959 1/20 0.31
HRH3 Q9Y5N1 1/20 0.31
NPC1 O15118 1/20 0.31
CASP3 P42574 1/20 0.31
RAB9A P51151 1/20 0.31
SMN1; SMN2 Q16637 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6673596 0.96 GPR3 (0.34) GPR3HTR2ANPC1CASP3RAB9A
SCHEMBL5175634 0.85 GPR3 (0.46) GPR3HTR2APOLBACHECHRM2
SCHEMBL4651299 0.84 GPR3 (0.34) GPR3HTR2ANPC1CASP3RAB9A
Hydrochloric Acid SCHEMBL6559595 0.81 GPR3 (0.43) GPR3HTR2APOLBACHECHRM2
Hydrochloric Acid SCHEMBL6559588 0.81 GPR3 (0.43) GPR3HTR2APOLBACHECHRM2
SCHEMBL7527136 0.81 GPR3 (0.32) GPR3NPC1CASP3RAB9ASMN1; SMN2
SCHEMBL19506959 0.79 GPR3 (0.30) GPR3
SCHEMBL23141276 0.74
SCHEMBL29897876 0.74
SCHEMBL7630038 0.74

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6297333-B1 METALLOCENE TRANSITION METAL COMPOUND HAVING AN INDENYL GROUP AND A FLUORENYL GROUP AS LIGANDS, SPECIFIC SUBSTITUENT ON A SPECIFIC POSITION OF THE INDENYL GROUP GIVES HIGH MOLECULAR WEIGHT AND HIGH ACTIVITY MITSUI CHEMICALS INC (JP) 2001-10-02 US disclosed
US-6004897-A TRANSITION METAL INDENE-FLUORINE COMPLEX COORDINATION CATALYST WITH ORGANOALUMINUM AND ALUMOXANE COMPOUNDS MITSUI CHEMICALS, INC. (JP) 1999-12-21 US disclosed
EP-0754698-A2 An olefin polymerization catalyst and a process for preparing olefin polymer MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) 1997-01-22 EP disclosed