Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 4/20 | 0.36 |
| ▸ | DRD4 | P21917 | 1/20 | 0.36 |
| ▸ | DRD3 | P35462 | 1/20 | 0.36 |
| ▸ | SMYD3 | Q9H7B4 | 1/20 | 0.34 |
| ▸ | FYN | P06241 | 1/20 | 0.33 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.33 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.33 |
| ▸ | DYRK1A | Q13627 | 2/20 | 0.32 |
| ▸ | CLK1 | P49759 | 1/20 | 0.32 |
| ▸ | DYRK1B | Q9Y463 | 1/20 | 0.32 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.31 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.31 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.31 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.31 |
| ▸ | PFKFB3 | Q16875 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Propylamine SCHEMBL6560092 | 0.91 | MAPT (0.41) | DRD2DRD4DRD3SMYD3KCNH2 | |
| SCHEMBL6560912 | 0.70 | DRD2 (0.51) | DRD2DRD4DRD3 | |
| SCHEMBL6648826 | 0.67 | ALDH1A1 (0.39) | DRD2DYRK1ACLK1DYRK1BSLC6A2 | |
| SCHEMBL10336932 | 0.67 | ALDH1A1 (0.39) | DRD2DYRK1ACLK1DYRK1BSLC6A2 | |
| Benzo[D]Thiazole SCHEMBL28239011 | 0.66 | ALDH1A1 (0.70) | SMYD3TAS1R3TAS1R1DYRK1APFKFB3 | |
| SCHEMBL6558776 | 0.65 | DRD2 (0.54) | DRD2DRD4DRD3FYNKCNH2 | |
| SCHEMBL6558739 | 0.65 | DRD2 (0.54) | DRD2DRD4DRD3KCNH2 | |
| SCHEMBL4296143 | 0.64 | ALDH1A1 (0.52) | TAS1R3TAS1R1DYRK1ACLK1DYRK1B | |
| SCHEMBL4560336 | 0.62 | ALDH1A1 (0.50) | TAS1R3TAS1R1DYRK1ACLK1DYRK1B | |
| SCHEMBL7393183 | 0.62 | DRD2 (0.61) | DRD2DRD4DRD3KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1091946-B1 | NEW 2-AMINOTHIAZOL-FUSED 2-AMINOINDANS AND 2-AMINOTETRALINS AND THEIR USE | WIKSTROEM HAKAN VILHELM (NL) | 2004-03-17 | — | — | EP | disclosed |
| US-6291494-B1 | 2-aminothiazol-fused 2-aminoindans and 2-aminotetralins and their use | ASTRAZENECA AB (SE) | 2001-09-18 | — | — | US | disclosed |