Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | NPC1 | O15118 | 4/20 | 0.45 |
| ▸ | RAB9A | P51151 | 4/20 | 0.45 |
| ▸ | GSK3B | P49841 | 4/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | HTT | P42858 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.41 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.41 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.40 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.40 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.40 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.40 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.40 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.40 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Iodide SCHEMBL5949288 | 0.99 | L3MBTL1 (0.46) | L3MBTL1MAPTKMT2ANPC1RAB9A | |
| SCHEMBL6562246 | 0.92 | GSK3B (0.48) | L3MBTL1MAPTKMT2ANPC1RAB9A | |
| Iodide SCHEMBL5949629 | 0.91 | GSK3B (0.47) | L3MBTL1MAPTKMT2ANPC1RAB9A | |
| SCHEMBL6560743 | 0.88 | L3MBTL1 (0.58) | L3MBTL1MAPTKMT2ANPC1RAB9A | |
| SCHEMBL6561355 | 0.88 | RAB9A (0.49) | L3MBTL1MAPTKMT2ANPC1RAB9A | |
| Trifluoromethanesulfonic Acid SCHEMBL5949333 | 0.88 | KCNH2 (0.44) | L3MBTL1MAPTKMT2ANPC1RAB9A | |
| Iodide SCHEMBL5949328 | 0.87 | RAB9A (0.48) | L3MBTL1MAPTKMT2ANPC1RAB9A | |
| Iodide SCHEMBL5949340 | 0.87 | L3MBTL1 (0.57) | L3MBTL1MAPTKMT2ANPC1RAB9A | |
| Trifluoromethanesulfonic Acid SCHEMBL5948927 | 0.80 | KCNH2 (0.49) | MAPTKMT2AGSK3BKCNH2MEN1 | |
| SCHEMBL8103360 | 0.77 | MAPT (0.48) | L3MBTL1MAPTKMT2ANPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1050531-B1 | Pyridine and piperidine derivatives for treating neurodegenerative diseases | SERVIER LAB (FR) | 2004-11-17 | — | — | EP | disclosed |
| EP-1050531-A1 | Pyridine and piperidine derivatives for treating neurodegenerative diseases | ADIR ET COMPAGNIE (FR) | 2000-11-08 | — | — | EP | disclosed |