Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.48 |
| ▸ | MEN1 | O00255 | 2/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.48 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.48 |
| ▸ | CES1 | P23141 | 1/20 | 0.48 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.46 |
| ▸ | GSK3B | P49841 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.45 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.45 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 2/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Iodide SCHEMBL5949218 | 0.98 | MAPT (0.47) | MAPTTDP1KMT2AKDM4EMAPK1 | |
| SCHEMBL6560513 | 0.92 | NPC1 (0.59) | MAPTTDP1KMT2AKDM4EMEN1 | |
| SCHEMBL6562193 | 0.90 | RAB9A (0.48) | MAPTKMT2AMAPK1MEN1SMN1; SMN2 | |
| SCHEMBL6560743 | 0.90 | L3MBTL1 (0.58) | MAPTKMT2AKDM4EMAPK1MEN1 | |
| SCHEMBL6561355 | 0.90 | RAB9A (0.49) | MAPTTDP1KMT2AKDM4EMEN1 | |
| Iodide SCHEMBL5949442 | 0.90 | NPC1 (0.57) | MAPTTDP1KMT2AKDM4EMEN1 | |
| Iodide SCHEMBL5948931 | 0.89 | RAB9A (0.47) | MAPTKMT2AKDM4EMAPK1MEN1 | |
| Iodide SCHEMBL5949328 | 0.89 | RAB9A (0.48) | MAPTTDP1KMT2AKDM4EMAPK1 | |
| Iodide SCHEMBL5949340 | 0.89 | L3MBTL1 (0.57) | MAPTKMT2AKDM4EMAPK1MEN1 | |
| SCHEMBL6561313 | 0.87 | CES2 (0.54) | KMT2AMEN1SMN1; SMN2CES1KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1050531-A1 | Pyridine and piperidine derivatives for treating neurodegenerative diseases | ADIR ET COMPAGNIE (FR) | 2000-11-08 | — | — | EP | disclosed |