Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPV1 | Q8NER1 | 5/20 | 0.42 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.37 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.37 |
| ▸ | CTSD | P07339 | 1/20 | 0.37 |
| ▸ | BACE1 | P56817 | 1/20 | 0.37 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | HTR2A | P28223 | 1/20 | 0.36 |
| ▸ | DRD3 | P35462 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31595501 | 0.81 | TRPV1 (0.45) | TRPV1CTSDBACE1HTR2A | |
| SCHEMBL12927161 | 0.79 | TRPV1 (0.44) | TRPV1CTSDBACE1DRD3 | |
| SCHEMBL6559589 | 0.77 | TRPV1 (0.52) | TRPV1 | |
| SCHEMBL6559512 | 0.74 | TRPV1 (0.52) | TRPV1 | |
| SCHEMBL6937196 | 0.74 | TRPV1 (0.47) | TRPV1CYP11B1CYP11B2 | |
| SCHEMBL6344681 | 0.74 | DRD2 (0.44) | CYP11B1CYP11B2HTR2ADRD3 | |
| SCHEMBL6340312 | 0.74 | CYP11B1 (0.40) | CYP11B1CYP11B2CTSDBACE1HTR2A | |
| SCHEMBL6560802 | 0.73 | TRPV1 (0.51) | TRPV1CTSDBACE1 | |
| SCHEMBL10883982 | 0.73 | TRPV1 (0.53) | TRPV1CTSDBACE1 | |
| SCHEMBL7857620 | 0.73 | ENPP2 (0.41) | TRPV1CTSDBACE1HTR2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1204134-C | Sulfamine-substituted benzodihydopyran, preparation method, use as medicine or diagnostic reagent and medicine containing same | HOECHST AG (DE) | 2005-06-01 | — | — | CN | disclosed |
| EP-0807629-B1 | Sulfonamido substituted chromane derivatives, method for their preparation, their use as medicaments or diagnostic agents aswell as medicaments containing them | AVENTIS PHARMA GMBH (DE) | 2004-03-03 | — | — | EP | disclosed |
| US-6191164-B1 | POTASSIUM CHANNEL MODULATORS; ANTIULCER AGENTS | HOECHST AKTIENGESELLSCHAFT (DE) | 2001-02-20 | — | — | US | disclosed |
| CN-1169429-A | Sulfamine-substituted benzodihydopyran, preparation method, use as medicine or diagnostic reagent and medicine containing same | HOECHST AG (DE) | 1998-01-07 | — | — | CN | disclosed |
| EP-0807629-A1 | Sulfonamido substituted chromane derivatives, method for their preparation, their use as medicaments or diagnostic agents aswell as medicaments containing them | HOECHST AKTIENGESELLSCHAFT (DE) | 1997-11-19 | — | — | EP | disclosed |