SCHEMBL6560170

SCHEMBL6560170

CCCC=Nc1ccc(OC)cc1

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
S100B P04271 1/20 0.46
ALDH1A1 P00352 2/20 0.44
ACHE P22303 1/20 0.44
CA12 O43570 2/20 0.42
CA2 P00918 2/20 0.42
CA9 Q16790 2/20 0.42
CA1 P00915 1/20 0.42
CA7 P43166 1/20 0.42
CA14 Q9ULX7 1/20 0.42
GAA P10253 1/20 0.41
MAPT P10636 1/20 0.41
NOS3 P29474 4/20 0.41
HTR3E A5X5Y0 1/20 0.41
HTR3B O95264 1/20 0.41
HTR3A P46098 1/20 0.41
HTR3D Q70Z44 1/20 0.41
HTR3C Q8WXA8 1/20 0.41
NOS1 P29475 2/20 0.41
NOS2 P35228 2/20 0.41
PTGS2 P35354 2/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12534124 0.84 S100B (0.49) S100BALDH1A1ACHECA12CA2
SCHEMBL7763844 0.84 S100B (0.49) S100BALDH1A1ACHECA12CA2
SCHEMBL9640860 0.79 CA12 (0.55) S100BALDH1A1ACHECA12CA2
SCHEMBL12616347 0.79 CA12 (0.55) S100BALDH1A1ACHECA12CA2
SCHEMBL12617752 0.79 CA12 (0.55) S100BALDH1A1ACHECA12CA2
SCHEMBL14129066 0.78 S100B (0.41) S100BALDH1A1ACHECA12CA2
SCHEMBL23644537 0.76 MAPT (0.43) ALDH1A1CA12CA2CA9CA1
SCHEMBL12653950 0.76 CYP2C9 (0.53) ALDH1A1CA2GAAMAPTPTGS2
SCHEMBL18489547 0.76 CYP2C9 (0.40) S100BALDH1A1GAAMAPTNOS1
SCHEMBL7730052 0.76 S100B (0.45) S100BALDH1A1ACHECA12CA2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1110941-B1 Process for the codimerisation of polyunsaturated fatty compounds and olefines with iron complexes INST FRANCAIS DU PETROLE (FR) 2004-03-17 EP disclosed
EP-1110941-A1 Process for the codimerisation of polyunsaturated fatty compounds and olefines with iron complexes INSTITUT FRANCAIS DU PETROLE (FR) 2001-06-27 EP disclosed