SCHEMBL9640860

SCHEMBL9640860

COc1ccc(N=CC=Nc2ccc(OC)cc2)cc1

nearest known ligand 0.55

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA12 O43570 2/20 0.55
CA2 P00918 2/20 0.55
CA9 Q16790 2/20 0.55
CA1 P00915 1/20 0.55
CA7 P43166 1/20 0.55
CA14 Q9ULX7 1/20 0.55
S100B P04271 2/20 0.55
ACHE P22303 2/20 0.52
ALDH1A1 P00352 2/20 0.52
NOS3 P29474 2/20 0.50
HTR3E A5X5Y0 1/20 0.50
HTR3B O95264 1/20 0.50
HTR3A P46098 1/20 0.50
HTR3D Q70Z44 1/20 0.50
HTR3C Q8WXA8 1/20 0.50
PTGS2 P35354 2/20 0.47
PTGS1 P23219 1/20 0.47
KMT2A Q03164 1/20 0.47
TP53 P04637 1/20 0.47
TSHR P16473 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12616347 1.00 CA12 (0.55) CA12CA2CA9CA1CA7
SCHEMBL12617752 1.00 CA12 (0.55) CA12CA2CA9CA1CA7
SCHEMBL14382844 0.91 ACHE (0.62) CA12CA2CA9CA1CA7
SCHEMBL14459430 0.87 S100B (0.49) CA12CA2CA9CA1CA7
SCHEMBL14459258 0.87 S100B (0.49) CA12CA2CA9CA1CA7
SCHEMBL6858465 0.85 S100B (0.47) CA12CA2CA9CA1CA7
SCHEMBL22861516 0.85 S100B (0.47) CA12CA2CA9CA1CA7
SCHEMBL22549462 0.83 S100B (0.50) CA12CA2CA9CA1CA7
SCHEMBL12432939 0.83 NOS3 (0.50) CA12CA2CA9CA1CA7
SCHEMBL13302734 0.83 S100B (0.53) CA12CA2CA9CA1CA7

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0280373-B1 PROCESS FOR THE DIMERIZATION OF OLEFINS SHELL INTERNATIONALE RESEARCHMAATSCHAPPIJ B.V. (NL) 1992-08-12 EP disclosed
EP-0206367-B1 PROCESS FOR THE DIMERIZATION OF ETHYLENICALLY UNSATURATED COMPOUNDS SHELL INTERNATIONALE RESEARCHMAATSCHAPPIJ B.V. (NL) 1990-06-27 EP disclosed
US-4859646-A Process for the dimerization of olefins SHELL OIL COMPANY (US) 1989-08-22 US disclosed
US-4806647-A PALLADIUM(II) COMPOUND, CHELATE LIGAND, PROTONIC ACID AND SALT SHELL OIL COMPANY (US) 1989-02-21 US disclosed
EP-0170311-B1 PROCESS FOR THE DIMERIZATION OF OLEFINS SHELL INTERNATIONALE RESEARCHMAATSCHAPPIJ B.V. (NL) 1989-02-01 EP disclosed
US-4692548-A DIMERIZATION OF ETHYLENICALLY UNSATURATED COMPOUNDS SHELL OIL COMPANY (US) 1987-09-08 US disclosed
US-4634793-A PALLADIUM CATALYST SYSTEM SHELL OIL COMPANY (US) 1987-01-06 US disclosed
EP-0206367-A2 Process for the dimerization of ethylenically unsaturated compounds SHELL INTERNATIONALE RESEARCHMAATSCHAPPIJ B.V. (NL) 1986-12-30 EP disclosed
EP-0170311-A2 Process for the dimerization of olefins SHELL INTERNATIONALE RESEARCHMAATSCHAPPIJ B.V. (NL) 1986-02-05 EP disclosed
US-4066609-A GLASS FABRIC OR FIBER CIBA-GEIGY CORPORATION (US) 1978-01-03 US disclosed
US-3993630-A Polyimide, polyamide-imide or polyamide-acids with olefin end groups in combination with a reactive Schiff base compound CIBA-GEIGY CORPORATION (US) 1976-11-23 US disclosed
US-3944525-A Crosslinked resins prepared from an N,N'-bis-imide and a schiff base CIBA-GEIGY CORPORATION (US) 1976-03-16 US disclosed