Di(Hydroxyethyl)Ether

Di(Hydroxyethyl)Ether

SCHEMBL6560427

CC(C)Oc1ccccc1.OCCOCCO

nearest known ligand 0.50

Full drug profile on Sugi Atlas →

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.50
RECQL P46063 1/20 0.50
NPC1 O15118 1/20 0.45
RAB9A P51151 1/20 0.45
KMT2A Q03164 3/20 0.45
LMNA P02545 2/20 0.45
GAA P10253 2/20 0.45
MEN1 O00255 2/20 0.45
TP53 P04637 1/20 0.45
CNR2 P34972 1/20 0.42
MTNR1A P48039 1/20 0.41
MTNR1B P49286 1/20 0.41
KDM4E B2RXH2 1/20 0.41
NSD2 O96028 1/20 0.41
SMN1; SMN2 Q16637 1/20 0.41
POLB P06746 1/20 0.41
RXRA P19793 1/20 0.39
RXRB P28702 1/20 0.39
PARP10 Q53GL7 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Ethylene Glycol SCHEMBL6564401 0.88 ALDH1A1 (0.50) ALDH1A1RECQLNPC1RAB9AKMT2A
Triethylene Glycol SCHEMBL21617947 0.85 ALDH1A1 (0.47) ALDH1A1RECQLKMT2ALMNAGAA
SCHEMBL12394 0.81 KMT2A (0.54) ALDH1A1NPC1RAB9AKMT2ALMNA
Propylene Glycol SCHEMBL6560419 0.80 LMNA (0.53) ALDH1A1NPC1RAB9AKMT2ALMNA
Diethylene Glycol Monoethyl Ether SCHEMBL11820337 0.80 ALDH1A1 (0.44) ALDH1A1RECQLKMT2ALMNAMEN1
Ethylene Glycol SCHEMBL6558622 0.79 NPC1 (0.44) ALDH1A1RECQLNPC1RAB9AKMT2A
Di(Hydroxyethyl)Ether SCHEMBL29072093 0.79 RECQL (0.48) ALDH1A1RECQLKMT2ALMNAGAA
Ammonia Solution, Strong SCHEMBL8909178 0.79 KMT2A (0.52) ALDH1A1NPC1RAB9AKMT2ALMNA
Hydrogen Sulfide SCHEMBL27992657 0.79 KMT2A (0.52) ALDH1A1NPC1RAB9AKMT2ALMNA
Phosphine SCHEMBL28772208 0.79 KMT2A (0.52) ALDH1A1NPC1RAB9AKMT2ALMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0735403-B1 Liquid crystal orienting agent JSR CORP (JP) 2004-03-17 EP disclosed
US-5700860-A Liquid crystal orienting agent JAPAN SYNTHETIC RUBBER CO., LTD. (JP) 1997-12-23 US disclosed
EP-0735403-A1 Liquid crystal orienting agent JAPAN SYNTHETIC RUBBER CO., LTD. (JP) 1996-10-02 EP disclosed