Ether

Ether

SCHEMBL6560461

C=CC.C=CC.CCC(=O)Oc1ccccc1.CCOCC.OCCO

nearest known ligand 0.51

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ELANE P08246 1/20 0.51
KMT2A Q03164 5/20 0.44
ESR1 P03372 2/20 0.44
HIF1A Q16665 2/20 0.44
SMN1; SMN2 Q16637 2/20 0.44
RECQL P46063 1/20 0.44
ACHE P22303 2/20 0.42
RAB9A P51151 2/20 0.40
HTT P42858 2/20 0.40
LMNA P02545 1/20 0.40
MAPT P10636 4/20 0.39
NPC1 O15118 1/20 0.39
NFKB1 P19838 1/20 0.39
NFKB2 Q00653 1/20 0.39
RELA Q04206 1/20 0.39
MEN1 O00255 2/20 0.39
TP53 P04637 1/20 0.39
CYP19A1 P11511 1/20 0.38
LGALS8 O00214 1/20 0.37
ALDH1A1 P00352 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Ether SCHEMBL6560472 0.92 ELANE (0.58) ELANEKMT2AESR1HIF1ASMN1; SMN2
Acetic Acid Phenyl Ester SCHEMBL896830 0.87 ELANE (0.46) ELANEKMT2ASMN1; SMN2ACHERAB9A
Ether SCHEMBL12971074 0.86 KMT2A (0.40) ELANEKMT2AESR1SMN1; SMN2HTT
Ethylene Glycol SCHEMBL28649244 0.86 ELANE (0.66) ELANEKMT2AESR1HIF1ASMN1; SMN2
Di(Hydroxyethyl)Ether SCHEMBL6560874 0.85 ELANE (0.54) ELANEKMT2AESR1HIF1ASMN1; SMN2
Ether SCHEMBL12971186 0.84 MAPT (0.47) KMT2ASMN1; SMN2RAB9ALMNAMAPT
Ether SCHEMBL37233 0.83 THRB (0.51) ELANEKMT2ASMN1; SMN2RECQLLMNA
Ether SCHEMBL2818434 0.82 THRB (0.50) ELANEKMT2ASMN1; SMN2RECQLLMNA
Ether SCHEMBL6578176 0.82 THRB (0.50) ELANEKMT2ASMN1; SMN2RECQLLMNA
Propylene Glycol SCHEMBL6560844 0.81 ELANE (0.53) ELANEKMT2AESR1HIF1ASMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0735403-B1 Liquid crystal orienting agent JSR CORP (JP) 2004-03-17 EP disclosed
US-5700860-A Liquid crystal orienting agent JAPAN SYNTHETIC RUBBER CO., LTD. (JP) 1997-12-23 US disclosed
EP-0735403-A1 Liquid crystal orienting agent JAPAN SYNTHETIC RUBBER CO., LTD. (JP) 1996-10-02 EP disclosed