Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 3/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.51 |
| ▸ | RAB9A | P51151 | 2/20 | 0.51 |
| ▸ | GCGR | P47871 | 1/20 | 0.51 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.49 |
| ▸ | PLK1 | P53350 | 2/20 | 0.48 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.46 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.44 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | CNR2 | P34972 | 3/20 | 0.44 |
| ▸ | CNR1 | P21554 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6561900 | 1.00 | NPC1 (0.51) | NPC1KMT2ARAB9AGCGRMTNR1A | |
| SCHEMBL1176798 | 0.86 | NPC1 (0.51) | NPC1KMT2ARAB9AGCGRCACNA1B | |
| SCHEMBL6561769 | 0.85 | NPC1 (0.43) | NPC1KMT2ARAB9AGCGRMTNR1A | |
| SCHEMBL6561831 | 0.85 | NPC1 (0.43) | NPC1KMT2ARAB9AGCGRMTNR1A | |
| SCHEMBL6560697 | 0.83 | NPC1 (0.51) | NPC1KMT2ARAB9APLK1ALDH1A1 | |
| SCHEMBL6561877 | 0.83 | NPC1 (0.51) | NPC1KMT2ARAB9APLK1ALDH1A1 | |
| SCHEMBL6562127 | 0.81 | PLK1 (0.47) | NPC1RAB9APLK1ALDH1A1SMN1; SMN2 | |
| SCHEMBL6561874 | 0.81 | PLK1 (0.47) | NPC1RAB9APLK1ALDH1A1SMN1; SMN2 | |
| SCHEMBL6560672 | 0.80 | CACNA1B (0.52) | NPC1KMT2ARAB9AGCGRMTNR1A | |
| SCHEMBL9856912 | 0.80 | GCGR (0.67) | NPC1KMT2ARAB9AGCGRMTNR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0944581-A4 | PROCESS OF PREPARING SUBSTITUTED ACRYLAMIDES | LILLY CO ELI (US) | 2004-09-08 | — | — | EP | disclosed |
| EP-0944581-A1 | PROCESS OF PREPARING SUBSTITUTED ACRYLAMIDES | ELI LILLY AND COMPANY (US) | 1999-09-29 | — | — | EP | disclosed |
| WO-1998022429-A1 | PROCESS OF PREPARING SUBSTITUTED ACRYLAMIDES | ELI LILLY AND COMPANY (US) | 1998-05-28 | — | — | WO | disclosed |