Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CACNA1B | Q00975 | 1/20 | 0.52 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.52 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | DRD4 | P21917 | 1/20 | 0.47 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.46 |
| ▸ | GCGR | P47871 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | USP2 | O75604 | 1/20 | 0.45 |
| ▸ | TP53 | P04637 | 1/20 | 0.45 |
| ▸ | PLK1 | P53350 | 1/20 | 0.45 |
| ▸ | NPC1 | O15118 | 2/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6561772 | 0.87 | POLB (0.44) | CACNA1BAPBA1PTPN1ALDH1A1KMT2A | |
| SCHEMBL6560700 | 0.84 | NPC1 (0.51) | ALDH1A1KMT2AMEN1KDM4EL3MBTL1 | |
| SCHEMBL6561900 | 0.80 | NPC1 (0.51) | CACNA1BAPBA1ALDH1A1KMT2AMEN1 | |
| SCHEMBL6560669 | 0.80 | NPC1 (0.51) | CACNA1BAPBA1ALDH1A1KMT2AMEN1 | |
| SCHEMBL16162267 | 0.79 | TP53 (0.67) | CACNA1BAPBA1PTPN1ALDH1A1KMT2A | |
| SCHEMBL6561872 | 0.74 | ALDH1A1 (0.52) | ALDH1A1KMT2AMEN1KDM4EMAPT | |
| SCHEMBL9856912 | 0.71 | GCGR (0.67) | CACNA1BAPBA1ALDH1A1KMT2AMTNR1A | |
| SCHEMBL27773350 | 0.71 | CACNA1B (0.50) | CACNA1BAPBA1PTPN1ALDH1A1KMT2A | |
| SCHEMBL16162265 | 0.69 | POLB (0.63) | PTPN1ALDH1A1KMT2AMEN1KDM4E | |
| SCHEMBL28813458 | 0.69 | CACNA1B (0.59) | CACNA1BAPBA1ALDH1A1KMT2AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0944581-A4 | PROCESS OF PREPARING SUBSTITUTED ACRYLAMIDES | LILLY CO ELI (US) | 2004-09-08 | — | — | EP | disclosed |
| EP-0944581-A1 | PROCESS OF PREPARING SUBSTITUTED ACRYLAMIDES | ELI LILLY AND COMPANY (US) | 1999-09-29 | — | — | EP | disclosed |
| WO-1998022429-A1 | PROCESS OF PREPARING SUBSTITUTED ACRYLAMIDES | ELI LILLY AND COMPANY (US) | 1998-05-28 | — | — | WO | disclosed |