SCHEMBL6560711

SCHEMBL6560711

CCOC(=O)C(Cl)CCCl

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 6/20 0.40
HSD17B10 Q99714 2/20 0.39
LMNA P02545 1/20 0.39
ALOX15 P16050 3/20 0.37
MGAM O43451 1/20 0.37
GAA P10253 1/20 0.37
SI P14410 1/20 0.37
MGAM2 Q2M2H8 1/20 0.37
SOAT1 P35610 1/20 0.37
SMN1; SMN2 Q16637 2/20 0.36
L3MBTL1 Q9Y468 1/20 0.35
TRPA1 O75762 1/20 0.34
POLB P06746 2/20 0.34
HTT P42858 1/20 0.34
CPB2 Q96IY4 1/20 0.34
KMT2A Q03164 3/20 0.33
CYP3A4 P08684 2/20 0.33
CYP2D6 P10635 1/20 0.33
CYP2C9 P11712 1/20 0.33
CYP2C19 P33261 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2868181 0.88 ALDH1A1 (0.46) ALDH1A1HSD17B10LMNAALOX15MGAM
SCHEMBL7971410 0.87 SMN1; SMN2 (0.41) ALDH1A1HSD17B10LMNAALOX15MGAM
SCHEMBL7973321 0.85 SMN1; SMN2 (0.40) ALDH1A1HSD17B10LMNAALOX15MGAM
SCHEMBL27631184 0.84 ALDH1A1 (0.42) ALDH1A1HSD17B10LMNAALOX15MGAM
SCHEMBL2858639 0.84 CPB2 (0.43) ALDH1A1HSD17B10LMNAALOX15MGAM
SCHEMBL8149342 0.84 ALDH1A1 (0.42) ALDH1A1HSD17B10LMNAALOX15MGAM
SCHEMBL6755582 0.84 ALDH1A1 (0.42) ALDH1A1HSD17B10LMNAALOX15MGAM
SCHEMBL29072823 0.84 CPB2 (0.41) ALDH1A1HSD17B10LMNASMN1; SMN2L3MBTL1
SCHEMBL16860621 0.84 CPB2 (0.41) ALDH1A1HSD17B10LMNASMN1; SMN2L3MBTL1
SCHEMBL27842619 0.83 HCAR2 (0.35) ALDH1A1LMNASMN1; SMN2TSHRTDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 30 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-102532368-B Rare earth catalyst and method for polymerizing conjugated diene by using same UNIV BEIJING CHEMICAL 2014-04-02 CN claimed
CN-102260362-B Atactic multiblock styrene polymer and preparation method thereof UNIV BEIJING CHEMICAL 2013-04-10 CN claimed
CN-102532368-A Rare earth catalyst and method for polymerizing conjugated diene by using same UNIV BEIJING CHEMICAL 2012-07-04 CN claimed
CN-101955567-B Catalysis system and method for preparing diolefin copolymer elastomer CHINA PETROLEUM & CHEMICAL 2012-06-27 CN claimed
CN-101927186-B Rare earth catalyst system and method for preparing high cis-1,4-polyisoprene UNIV BEIJING CHEMICAL 2012-01-04 CN claimed
CN-102260362-A Atactic multiblock styrene polymer and preparation method thereof 2011-11-30 CN claimed
CN-101955567-A Catalysis system and method for preparing diolefin copolymer elastomer CHINA PETROLEUM & CHEMICAL 2011-01-26 CN claimed
CN-101927186-A Rare earth catalyst system and method for preparing high cis-1,4-polyisoprene UNIV BEIJING CHEMICAL 2010-12-29 CN claimed
CN-100448898-C Rare-earth catalyst and conjugated diene polymerization process CHINA PETROLEUM & CHEMICAL (CN) 2009-01-07 CN claimed
CN-1840552-A Rare-earth catalyst and conjugated diene polymerization process CHINA PETROLEUM & CHEMICAL (CN) 2006-10-04 CN claimed
CN-102532368-B Rare earth catalyst and method for polymerizing conjugated diene by using same UNIV BEIJING CHEMICAL 2014-04-02 CN disclosed
CN-102260362-B Atactic multiblock styrene polymer and preparation method thereof UNIV BEIJING CHEMICAL 2013-04-10 CN disclosed
CN-102532368-A Rare earth catalyst and method for polymerizing conjugated diene by using same UNIV BEIJING CHEMICAL 2012-07-04 CN disclosed
CN-101955567-B Catalysis system and method for preparing diolefin copolymer elastomer CHINA PETROLEUM & CHEMICAL 2012-06-27 CN disclosed
CN-101927186-B Rare earth catalyst system and method for preparing high cis-1,4-polyisoprene UNIV BEIJING CHEMICAL 2012-01-04 CN disclosed
US-5180418-A HERBICIDALLY ACTIVE THIADIAZABICYCLONONANES AND NONENES CIBA-GEIGY CORPORATION (US) 1993-01-19 US disclosed
US-4521344-A Cyano-dicarboxylate MONSANTO COMPANY (US) 1985-06-04 US disclosed
US-4514340-A Cyano-polycarboxylates MONSANTO COMPANY (US) 1985-04-30 US disclosed
US-4442298-A Chemical synthesis of ethylene/maleic anhydride dimer with phenylethyl end group MONSANTO COMPANY (US) 1984-04-10 US disclosed
US-4234744-A Process for the production of aminoacid hydrochlorides/or diaminoacid dihydrochlorides DEUTSCHE GOLD- UND SILBER SCHEIDEANSTALT VORMALS ROESSLER (DE) 1980-11-18 US disclosed