Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATM | Q13315 | 1/20 | 0.56 |
| ▸ | TOP2A | P11388 | 2/20 | 0.47 |
| ▸ | TOP2B | Q02880 | 2/20 | 0.47 |
| ▸ | TACR1 | P25103 | 1/20 | 0.44 |
| ▸ | CTSL | P07711 | 1/20 | 0.44 |
| ▸ | CTSS | P25774 | 1/20 | 0.44 |
| ▸ | ELANE | P08246 | 2/20 | 0.44 |
| ▸ | CTSK | P43235 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6558452 | 0.89 | ATM (0.51) | ATMCTSLCTSSCTSK | |
| SCHEMBL6560431 | 0.89 | ATM (0.51) | ATMTACR1CTSLCTSSCTSK | |
| SCHEMBL8425338 | 0.88 | ATM (0.50) | ATMTOP2ATOP2BTACR1ELANE | |
| SCHEMBL12221562 | 0.87 | ATM (0.51) | ATMTOP2ATOP2BTACR1 | |
| SCHEMBL8066055 | 0.86 | ATM (0.49) | ATMTACR1 | |
| SCHEMBL8143055 | 0.86 | ATM (0.49) | ATMTACR1 | |
| SCHEMBL6560404 | 0.85 | ATM (0.52) | ATMTACR1CTSLCTSSELANE | |
| SCHEMBL6560698 | 0.85 | ATM (0.52) | ATMTOP2ATOP2BTACR1CTSL | |
| SCHEMBL6560421 | 0.85 | ATM (0.52) | ATMTACR1CTSLCTSSELANE | |
| SCHEMBL2802686 | 0.85 | ATM (0.48) | ATMTACR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0948523-B1 | PEPTIDOMIMETIC INHIBITORS OF THE HUMAN CYTOMEGALOVIRUS PROTEASE | BOEHRINGER INGELHEIM CA LTD (CA) | 2004-03-17 | — | — | EP | disclosed |
| US-6291640-B1 | OLIGOPEPTIDES; SOLID PHASE SYNTHESIS | BOEHRINGER INGELHEIM LTD. (CA) | 2001-09-18 | — | — | US | disclosed |