Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATM | Q13315 | 1/20 | 0.51 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.43 |
| ▸ | CTSL | P07711 | 2/20 | 0.43 |
| ▸ | CTSS | P25774 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | CTSK | P43235 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | XDH | P47989 | 1/20 | 0.41 |
| ▸ | MAOB | P27338 | 1/20 | 0.41 |
| ▸ | TACR1 | P25103 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6558452 | 0.92 | ATM (0.51) | ATMCTSLCTSSCTSKXDH | |
| SCHEMBL8425338 | 0.89 | ATM (0.50) | ATMMAPTNPC1RAB9ATACR1 | |
| SCHEMBL6560715 | 0.89 | ATM (0.56) | ATMCTSLCTSSCTSKTACR1 | |
| SCHEMBL6560421 | 0.81 | ATM (0.52) | ATMCTSLCTSSCTSKNPC1 | |
| SCHEMBL6560698 | 0.81 | ATM (0.52) | ATMCTSLCTSSNPC1RAB9A | |
| SCHEMBL6560404 | 0.79 | ATM (0.52) | ATMCTSLCTSSTACR1 | |
| SCHEMBL9745868 | 0.78 | ATM (0.47) | ATMNPC1RAB9AMEN1KMT2A | |
| SCHEMBL9745860 | 0.78 | ATM (0.47) | ATMNPC1RAB9AMEN1KMT2A | |
| SCHEMBL8428050 | 0.78 | ATM (0.51) | ATMTACR1 | |
| SCHEMBL8066082 | 0.77 | TRPM8 (0.47) | ATMCTSLCTSSCTSKNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0948523-B1 | PEPTIDOMIMETIC INHIBITORS OF THE HUMAN CYTOMEGALOVIRUS PROTEASE | BOEHRINGER INGELHEIM CA LTD (CA) | 2004-03-17 | — | — | EP | disclosed |
| US-6291640-B1 | OLIGOPEPTIDES; SOLID PHASE SYNTHESIS | BOEHRINGER INGELHEIM LTD. (CA) | 2001-09-18 | — | — | US | disclosed |