Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATM | Q13315 | 1/20 | 0.52 |
| ▸ | TOP2A | P11388 | 2/20 | 0.46 |
| ▸ | TOP2B | Q02880 | 2/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | TACR1 | P25103 | 1/20 | 0.41 |
| ▸ | CASP1 | P29466 | 1/20 | 0.41 |
| ▸ | CTSL | P07711 | 1/20 | 0.41 |
| ▸ | CTSS | P25774 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8428050 | 0.89 | ATM (0.51) | ATMTOP2ATOP2BTACR1 | |
| SCHEMBL6560715 | 0.85 | ATM (0.56) | ATMTOP2ATOP2BTACR1CTSL | |
| SCHEMBL6560421 | 0.84 | ATM (0.52) | ATMNPC1RAB9ATACR1CTSL | |
| SCHEMBL6558452 | 0.81 | ATM (0.51) | ATMCTSLCTSS | |
| SCHEMBL6560431 | 0.81 | ATM (0.51) | ATMNPC1RAB9ATACR1CTSL | |
| SCHEMBL8425338 | 0.78 | ATM (0.50) | ATMTOP2ATOP2BNPC1RAB9A | |
| SCHEMBL6560404 | 0.76 | ATM (0.52) | ATMTACR1CTSLCTSS | |
| SCHEMBL7141233 | 0.74 | CASP1 (0.60) | ATMTOP2ATOP2BCASP1CTSL | |
| SCHEMBL7783393 | 0.73 | ATM (0.56) | ATMCASP1CTSLCTSS | |
| SCHEMBL23314896 | 0.73 | ATM (0.51) | ATMTOP2ATOP2BCTSLCTSS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0948523-B1 | PEPTIDOMIMETIC INHIBITORS OF THE HUMAN CYTOMEGALOVIRUS PROTEASE | BOEHRINGER INGELHEIM CA LTD (CA) | 2004-03-17 | — | — | EP | disclosed |
| US-6291640-B1 | OLIGOPEPTIDES; SOLID PHASE SYNTHESIS | BOEHRINGER INGELHEIM LTD. (CA) | 2001-09-18 | — | — | US | disclosed |