Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATM | Q13315 | 1/20 | 0.52 |
| ▸ | FAAH | O00519 | 3/20 | 0.44 |
| ▸ | DAGLA | Q9Y4D2 | 3/20 | 0.43 |
| ▸ | ELANE | P08246 | 2/20 | 0.43 |
| ▸ | TACR1 | P25103 | 1/20 | 0.41 |
| ▸ | CTSL | P07711 | 2/20 | 0.41 |
| ▸ | CTSS | P25774 | 2/20 | 0.41 |
| ▸ | CTSB | P07858 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7731860 | 0.85 | FAAH (0.46) | ATMFAAHDAGLAELANETACR1 | |
| SCHEMBL6560715 | 0.85 | ATM (0.56) | ATMELANETACR1CTSLCTSS | |
| SCHEMBL6560421 | 0.82 | ATM (0.52) | ATMELANETACR1CTSLCTSS | |
| SCHEMBL5947645 | 0.81 | NPC1 (0.41) | ATMFAAH | |
| SCHEMBL5947648 | 0.81 | NPC1 (0.41) | ATMFAAH | |
| SCHEMBL16492787 | 0.79 | ATM (0.54) | ATMELANECTSLCTSSCTSB | |
| SCHEMBL6558452 | 0.79 | ATM (0.51) | ATMCTSLCTSS | |
| SCHEMBL6560431 | 0.79 | ATM (0.51) | ATMTACR1CTSLCTSS | |
| SCHEMBL8425338 | 0.78 | ATM (0.50) | ATMELANETACR1 | |
| SCHEMBL6560698 | 0.76 | ATM (0.52) | ATMTACR1CTSLCTSS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0948523-B1 | PEPTIDOMIMETIC INHIBITORS OF THE HUMAN CYTOMEGALOVIRUS PROTEASE | BOEHRINGER INGELHEIM CA LTD (CA) | 2004-03-17 | — | — | EP | disclosed |
| US-6291640-B1 | OLIGOPEPTIDES; SOLID PHASE SYNTHESIS | BOEHRINGER INGELHEIM LTD. (CA) | 2001-09-18 | — | — | US | disclosed |