Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIN2D | O15399 | 1/20 | 0.44 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.44 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.44 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.44 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.43 |
| ▸ | PLAU | P00749 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | HSD17B1 | P14061 | 6/20 | 0.38 |
| ▸ | HSD17B2 | P37059 | 6/20 | 0.38 |
| ▸ | ESR1 | P03372 | 2/20 | 0.38 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.38 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | DNMT1 | P26358 | 1/20 | 0.36 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.36 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.36 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3282140 | 0.86 | PTPN1 (0.41) | CYP1A2PTPN1MEN1ALDH1A1KMT2A | |
| SCHEMBL430311 | 0.78 | CYP1A2 (0.59) | GRIN2DGRIN2AGRIN2BGRIN2CCTDSP1 | |
| SCHEMBL30323818 | 0.78 | CYP1A2 (0.59) | GRIN2DGRIN2AGRIN2BGRIN2CCTDSP1 | |
| SCHEMBL3280396 | 0.77 | PTPN22 (0.52) | CYP1A2PTPN1MEN1ALDH1A1KMT2A | |
| SCHEMBL6561997 | 0.75 | MEN1 (0.61) | MEN1ALDH1A1DNMT1CACNA1BAPBA1 | |
| SCHEMBL8385655 | 0.74 | PTPN22 (0.54) | GRIN2DGRIN2AGRIN2BGRIN2CCTDSP1 | |
| SCHEMBL17058714 | 0.73 | CYP1A2 (0.54) | GRIN2DGRIN2AGRIN2BGRIN2CCTDSP1 | |
| SCHEMBL28549486 | 0.72 | CES2 (0.44) | PLAUCYP1A2ESR2PTPN1MEN1 | |
| SCHEMBL29686167 | 0.72 | CYP1A2 (0.54) | GRIN2DGRIN2AGRIN2BGRIN2CCTDSP1 | |
| SCHEMBL9067119 | 0.72 | CYP1A2 (0.54) | GRIN2DGRIN2AGRIN2BGRIN2CCTDSP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1154778-B1 | PHARMACEUTICAL PREPARATION CONTAINING DITHRANOL | ESPARMA GMBH (DE) | 2004-05-12 | — | — | EP | disclosed |
| US-6413950-B1 | TOPICAL APPLICATION; SKIN DISORDERS | ESPARMA GMBH (DE) | 2002-07-02 | — | — | US | disclosed |