Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 4/20 | 0.61 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.61 |
| ▸ | DNMT1 | P26358 | 1/20 | 0.61 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.61 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.61 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.61 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.61 |
| ▸ | CDK2 | P24941 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | THRB | P10828 | 2/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.40 |
| ▸ | SNCA | P37840 | 2/20 | 0.40 |
| ▸ | RECQL | P46063 | 2/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | INPPL1 | O15357 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7738028 | 0.80 | ALDH1A1 (0.66) | MEN1KMT2AALDH1A1DNMT1CACNA1B | |
| SCHEMBL3198 | 0.78 | ALDH1A1 (1.00) | MEN1KMT2AALDH1A1DNMT1CACNA1B | |
| SCHEMBL6560733 | 0.75 | GRIN2D (0.44) | MEN1KMT2AALDH1A1DNMT1CACNA1B | |
| SCHEMBL3320154 | 0.74 | ALDH1A1 (0.91) | MEN1KMT2AALDH1A1DNMT1CACNA1B | |
| Acetic Acid SCHEMBL9119537 | 0.72 | KMT2A (0.76) | MEN1KMT2AALDH1A1DNMT1CACNA1B | |
| SCHEMBL3282140 | 0.71 | PTPN1 (0.41) | MEN1KMT2AALDH1A1HPGDHSD17B10 | |
| SCHEMBL6349397 | 0.68 | CDK2 (0.69) | MEN1KMT2AALDH1A1DNMT1CACNA1B | |
| SCHEMBL31037125 | 0.68 | CDK2 (0.69) | MEN1KMT2AALDH1A1DNMT1CACNA1B | |
| SCHEMBL3280396 | 0.68 | PTPN22 (0.52) | MEN1KMT2AALDH1A1MAPTHPGD | |
| SCHEMBL10714892 | 0.68 | ALDH1A1 (0.76) | MEN1KMT2AALDH1A1DNMT1CACNA1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1154778-B1 | PHARMACEUTICAL PREPARATION CONTAINING DITHRANOL | ESPARMA GMBH (DE) | 2004-05-12 | — | — | EP | disclosed |
| US-6413950-B1 | TOPICAL APPLICATION; SKIN DISORDERS | ESPARMA GMBH (DE) | 2002-07-02 | — | — | US | disclosed |