Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP4F2 | P78329 | 1/20 | 0.53 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.49 |
| ▸ | GLA | P06280 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.48 |
| ▸ | NPC1 | O15118 | 2/20 | 0.48 |
| ▸ | RAB9A | P51151 | 2/20 | 0.48 |
| ▸ | TP53 | P04637 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | EGFR | P00533 | 2/20 | 0.46 |
| ▸ | ERBB2 | P04626 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | GFER | P55789 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL502785 | 0.89 | CYP4F2 (0.63) | CYP4F2CYP4A11L3MBTL1KDM4EGLA | |
| SCHEMBL5536942 | 0.84 | CYP4F2 (0.58) | CYP4F2CYP4A11L3MBTL1KDM4EGLA | |
| SCHEMBL31324172 | 0.81 | SMN1; SMN2 (0.56) | CYP4F2CYP4A11L3MBTL1KDM4EGLA | |
| SCHEMBL4113212 | 0.80 | CYP4F2 (0.76) | CYP4F2CYP4A11L3MBTL1KDM4ESMN1; SMN2 | |
| SCHEMBL20547390 | 0.79 | CYP4F2 (0.51) | CYP4F2CYP4A11L3MBTL1KDM4EGLA | |
| SCHEMBL25326335 | 0.78 | TSHR (0.54) | CYP4F2CYP4A11L3MBTL1KDM4ESMN1; SMN2 | |
| SCHEMBL7960432 | 0.77 | L3MBTL1 (0.53) | CYP4F2CYP4A11L3MBTL1KDM4EGLA | |
| SCHEMBL6560775 | 0.76 | CYP4F2 (0.56) | CYP4F2CYP4A11L3MBTL1KDM4ESMN1; SMN2 | |
| SCHEMBL7633403 | 0.75 | L3MBTL1 (0.54) | L3MBTL1KDM4EGLASMN1; SMN2KMT2A | |
| SCHEMBL31324169 | 0.75 | SMN1; SMN2 (0.50) | CYP4F2CYP4A11L3MBTL1KDM4EGLA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1240154-A1 | SERINE PROTEASE INHIBITORS | Tularik Limited (GB) | 2002-09-18 | — | — | EP | disclosed |
| WO-2001044226-A1 | SERINE PROTEASE INHIBITORS | TULARIK LIMITED (GB) | 2001-06-21 | — | — | WO | disclosed |