Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | METAP2 | P50579 | 2/20 | 0.40 |
| ▸ | METAP1 | P53582 | 2/20 | 0.40 |
| ▸ | PSMB5 | P28074 | 6/20 | 0.40 |
| ▸ | CTSD | P07339 | 3/20 | 0.39 |
| ▸ | ITGB3 | P05106 | 2/20 | 0.38 |
| ▸ | ITGA2B | P08514 | 2/20 | 0.38 |
| ▸ | REN | P00797 | 4/20 | 0.37 |
| ▸ | MMP9 | P14780 | 1/20 | 0.37 |
| ▸ | MMP8 | P22894 | 1/20 | 0.37 |
| ▸ | MMP14 | P50281 | 1/20 | 0.37 |
| ▸ | PSMB1 | P20618 | 1/20 | 0.37 |
| ▸ | ITGAV | P06756 | 1/20 | 0.36 |
| ▸ | ITGB5 | P18084 | 1/20 | 0.36 |
| ▸ | ITGB6 | P18564 | 1/20 | 0.36 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.36 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.36 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.36 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.36 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.36 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6559318 | 0.91 | METAP2 (0.42) | METAP2METAP1PSMB5CTSDREN | |
| SCHEMBL6558478 | 0.88 | METAP2 (0.42) | METAP2METAP1CTSDREN | |
| SCHEMBL6560459 | 0.86 | METAP2 (0.40) | METAP2METAP1PSMB5CTSDREN | |
| Hydrochloric Acid SCHEMBL6559233 | 0.86 | METAP2 (0.41) | METAP2METAP1 | |
| SCHEMBL6559351 | 0.86 | METAP2 (0.45) | METAP2METAP1CTSDMMP9MMP8 | |
| SCHEMBL6560842 | 0.86 | METAP2 (0.43) | METAP2METAP1CTSDMMP9MMP8 | |
| SCHEMBL6558594 | 0.85 | METAP2 (0.45) | METAP2METAP1CTSDRENMMP9 | |
| Hydrochloric Acid SCHEMBL6559256 | 0.85 | METAP2 (0.45) | METAP2METAP1CTSDMMP9MMP8 | |
| SCHEMBL6559229 | 0.85 | METAP2 (0.45) | METAP2METAP1CTSDMMP9MMP8 | |
| SCHEMBL6558591 | 0.85 | METAP2 (0.45) | METAP2METAP1CTSDRENMMP9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0998488-B1 | POLYOL-AMINO ACID COMPOUNDS HAVING ANTI-HELICOBACTER PYLORI ACTIVITY | TAKEDA CHEMICAL INDUSTRIES LTD (JP) | 2004-03-17 | — | — | EP | disclosed |
| US-6423869-B1 | BACTERICIDES, ANTIULCER AGENTS | TAKEDA CHEMICAL INDUSTRIES, INC. (JP) | 2002-07-23 | — | — | US | disclosed |