Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSK | P43235 | 5/20 | 0.56 |
| ▸ | CTSS | P25774 | 5/20 | 0.56 |
| ▸ | CTSL | P07711 | 5/20 | 0.56 |
| ▸ | CTSB | P07858 | 3/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.55 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.55 |
| ▸ | ITGB3 | P05106 | 2/20 | 0.53 |
| ▸ | ITGAV | P06756 | 2/20 | 0.53 |
| ▸ | PPARG | P37231 | 1/20 | 0.52 |
| ▸ | PPARA | Q07869 | 1/20 | 0.52 |
| ▸ | TACR1 | P25103 | 2/20 | 0.51 |
| ▸ | KYNU | Q16719 | 1/20 | 0.51 |
| ▸ | SYK | P43405 | 1/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.51 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.51 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10561905 | 1.00 | CTSK (0.56) | CTSKCTSSCTSLCTSBALDH1A1 | |
| SCHEMBL6560900 | 1.00 | CTSK (0.56) | CTSKCTSSCTSLCTSBALDH1A1 | |
| SCHEMBL8438037 | 0.90 | ALDH1A1 (0.60) | CTSKCTSSCTSLCTSBALDH1A1 | |
| SCHEMBL8438035 | 0.90 | ALDH1A1 (0.60) | CTSKCTSSCTSLCTSBALDH1A1 | |
| SCHEMBL7329157 | 0.90 | CTSK (0.58) | CTSKCTSSCTSLCTSBITGB3 | |
| SCHEMBL1191975 | 0.90 | CTSK (0.58) | CTSKCTSSCTSLCTSBITGB3 | |
| SCHEMBL7370216 | 0.89 | CTSK (0.57) | CTSKCTSSCTSLCTSBALDH1A1 | |
| SCHEMBL20364117 | 0.89 | LMNA (0.51) | CTSKCTSSCTSLCTSBALDH1A1 | |
| SCHEMBL7370220 | 0.89 | CTSK (0.57) | CTSKCTSSCTSLCTSBALDH1A1 | |
| SCHEMBL20556200 | 0.86 | SIRT2 (0.57) | CTSKCTSSCTSLCTSBALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0998488-B1 | POLYOL-AMINO ACID COMPOUNDS HAVING ANTI-HELICOBACTER PYLORI ACTIVITY | TAKEDA CHEMICAL INDUSTRIES LTD (JP) | 2004-03-17 | — | — | EP | disclosed |
| US-6423869-B1 | BACTERICIDES, ANTIULCER AGENTS | TAKEDA CHEMICAL INDUSTRIES, INC. (JP) | 2002-07-23 | — | — | US | disclosed |