Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXRA | P19793 | 17/20 | 0.39 |
| ▸ | RXRB | P28702 | 5/20 | 0.38 |
| ▸ | RXRG | P48443 | 5/20 | 0.38 |
| ▸ | PPARG | P37231 | 2/20 | 0.38 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.38 |
| ▸ | RARG | P13631 | 4/20 | 0.37 |
| ▸ | RARA | P10276 | 3/20 | 0.37 |
| ▸ | RARB | P10826 | 3/20 | 0.37 |
| ▸ | CYP26A1 | O43174 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | CYP26B1 | Q9NR63 | 1/20 | 0.36 |
| ▸ | HNF4A | P41235 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6032738 | 0.91 | RARA (0.38) | RXRARXRBRXRGPPARGNR1H3 | |
| SCHEMBL6033101 | 0.88 | RXRA (0.47) | RXRARXRBRXRGPPARGNR1H3 | |
| SCHEMBL6032995 | 0.79 | RARA (0.40) | RXRARXRBRXRGPPARGNR1H3 | |
| SCHEMBL6528077 | 0.78 | — | — | |
| SCHEMBL6033022 | 0.75 | RARA (0.52) | RXRARXRBRXRGPPARGNR1H3 | |
| SCHEMBL6032986 | 0.75 | RXRA (0.59) | RXRARXRBRXRGPPARGNR1H3 | |
| SCHEMBL6033001 | 0.75 | RXRA (0.50) | RXRARXRBRXRGPPARGNR1H3 | |
| SCHEMBL8040267 | 0.74 | RXRA (0.32) | RXRARXRBRXRGRARGRARA | |
| SCHEMBL6473547 | 0.74 | RXRA (0.32) | RXRARXRBRXRGRARGRARA | |
| SCHEMBL6033103 | 0.73 | RXRA (0.45) | RXRARXRBRXRGPPARGNR1H3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1086080-B1 | DIARYLSELENIDE COMPOUNDS AND THEIR USE IN HUMAN OR VETERINARY MEDICINE AND IN COSMETICS | GALDERMA RES & DEV (FR) | 2004-08-25 | — | — | EP | disclosed |