Di(Hydroxyethyl)Ether

Di(Hydroxyethyl)Ether

SCHEMBL6560980

CCCOc1ccccc1.OCCOCCO

nearest known ligand 0.67

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.67
RECQL P46063 1/20 0.67
LTA4H P09960 3/20 0.53
LMNA P02545 3/20 0.51
KMT2A Q03164 2/20 0.51
MEN1 O00255 1/20 0.51
USP2 O75604 1/20 0.51
CYP3A4 P08684 1/20 0.51
MAPK1 P28482 1/20 0.51
CASP1 P29466 1/20 0.51
SMN1; SMN2 Q16637 1/20 0.51
SLCO1B3 Q9NPD5 1/20 0.51
SLCO1B1 Q9Y6L6 1/20 0.51
KCNA3 P22001 1/20 0.50
KDM4E B2RXH2 1/20 0.48
GAA P10253 1/20 0.47
CHRNB2 P17787 2/20 0.47
CHRNB4 P30926 2/20 0.47
CHRNA3 P32297 2/20 0.47
CHRNA7 P36544 2/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Phenoxyethanol SCHEMBL12100847 0.92 ALDH1A1 (0.79) ALDH1A1RECQLLTA4HLMNAKMT2A
Di(Hydroxyethyl)Ether SCHEMBL2485484 0.91 LTA4H (0.67) ALDH1A1RECQLLTA4HLMNAKMT2A
Ethylene Glycol SCHEMBL6560734 0.90 RECQL (0.68) ALDH1A1RECQLLTA4HLMNAKMT2A
Tetraethylene Glycol SCHEMBL2484429 0.89 ALDH1A1 (0.65) ALDH1A1RECQLLTA4HLMNAKMT2A
Triethylene Glycol SCHEMBL2487711 0.89 ALDH1A1 (0.65) ALDH1A1RECQLLTA4HLMNAKMT2A
Propane SCHEMBL27574924 0.89 ALDH1A1 (0.67) ALDH1A1RECQLLTA4HLMNAKMT2A
Phenoxyethanol SCHEMBL28208028 0.88 ALDH1A1 (0.86) ALDH1A1RECQLMAPK1KCNA3GAA
Di(Hydroxyethyl)Ether SCHEMBL2482141 0.87 LTA4H (0.64) ALDH1A1RECQLLTA4HLMNAKMT2A
Di(Hydroxyethyl)Ether SCHEMBL2485682 0.87 LTA4H (0.64) ALDH1A1RECQLLTA4HLMNAKMT2A
Phenoxyethanol SCHEMBL20163307 0.87 ALDH1A1 (0.66) ALDH1A1RECQLLTA4HLMNAKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0735403-B1 Liquid crystal orienting agent JSR CORP (JP) 2004-03-17 EP disclosed
US-5700860-A Liquid crystal orienting agent JAPAN SYNTHETIC RUBBER CO., LTD. (JP) 1997-12-23 US disclosed
EP-0735403-A1 Liquid crystal orienting agent JAPAN SYNTHETIC RUBBER CO., LTD. (JP) 1996-10-02 EP disclosed