Di(Hydroxyethyl)Ether

Di(Hydroxyethyl)Ether

SCHEMBL2482141

CCCCCCCCOc1ccccc1.OCCOCCO

nearest known ligand 0.64

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LTA4H P09960 2/20 0.64
ALDH1A1 P00352 3/20 0.63
MEN1 O00255 2/20 0.63
KMT2A Q03164 2/20 0.63
LMNA P02545 2/20 0.63
CYP3A4 P08684 2/20 0.63
MAPK1 P28482 2/20 0.63
SMN1; SMN2 Q16637 2/20 0.63
USP2 O75604 1/20 0.63
CASP1 P29466 1/20 0.63
SLCO1B3 Q9NPD5 1/20 0.63
SLCO1B1 Q9Y6L6 1/20 0.63
RECQL P46063 1/20 0.60
HTT P42858 2/20 0.58
THRB P10828 1/20 0.58
MAPT P10636 1/20 0.58
NR5A1 Q13285 1/20 0.56
MLNR O43193 1/20 0.55
NR1I2 O75469 1/20 0.55
ESR1 P03372 1/20 0.55

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Di(Hydroxyethyl)Ether SCHEMBL2485682 1.00 LTA4H (0.64) LTA4HALDH1A1MEN1KMT2ALMNA
Tetraethylene Glycol SCHEMBL2485875 0.98 ALDH1A1 (0.66) LTA4HALDH1A1MEN1KMT2ALMNA
Hexaethylene Glycol SCHEMBL11084821 0.98 ALDH1A1 (0.66) LTA4HALDH1A1MEN1KMT2ALMNA
Triethylene Glycol SCHEMBL2487016 0.98 ALDH1A1 (0.66) LTA4HALDH1A1MEN1KMT2ALMNA
SCHEMBL28323872 0.98 LTA4H (0.62) LTA4HALDH1A1MEN1KMT2ALMNA
Triethylene Glycol SCHEMBL2484230 0.98 ALDH1A1 (0.66) LTA4HALDH1A1MEN1KMT2ALMNA
Tetraethylene Glycol SCHEMBL2487341 0.98 ALDH1A1 (0.66) LTA4HALDH1A1MEN1KMT2ALMNA
Phenoxyethanol SCHEMBL2501075 0.97 ALDH1A1 (0.61) LTA4HALDH1A1MEN1KMT2ALMNA
Ethylene Glycol SCHEMBL28314132 0.97 ALDH1A1 (0.60) LTA4HALDH1A1MEN1KMT2ALMNA
SCHEMBL7913444 0.95 ALDH1A1 (0.67) LTA4HALDH1A1MEN1KMT2ALMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 28 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115449417-B Naphthalene compound dispersing agent, activated nano-primary pulp containing naphthalene compound dispersing agent and preparation method of naphthalene compound dispersing agent 神华准能资源综合开发有限公司 2023-07-14 CN disclosed
CN-114544564-A Morphine and methamphetamine combined determination reagent based on AIE nano-microspheres and preparation method and application thereof 广东省大湾区华南理工大学聚集诱导发光高等研究院 2022-05-27 CN disclosed
CN-110072856-B Process for producing alpha-hydroxycarboxylic acid dimer cyclic ester 株式会社吴羽 2022-03-15 CN disclosed
CN-111699179-B Method for producing cyclic ester 株式会社吴羽 2021-09-17 CN disclosed
CN-111741953-B Method for producing glycolide 株式会社吴羽 2021-05-28 CN disclosed
CN-111757873-A Method for producing glycolide 株式会社吴羽 2020-10-09 CN disclosed
CN-111741953-A Method for producing glycolide 株式会社吴羽 2020-10-02 CN disclosed
CN-111741952-A Method for producing glycolide 株式会社吴羽 2020-10-02 CN disclosed
CN-111699179-A Method for producing cyclic ester 株式会社吴羽 2020-09-22 CN disclosed
WO-2019181340-A1 GLYCOLIDE PRODUCTION METHOD 株式会社クレハ 2019-09-26 WO disclosed
EP-2377858-B1 METHOD FOR PRODUCING GLYCOLIDE KUREHA CORP (JP) 2014-04-30 EP disclosed
US-20120289713-A1 METHOD FOR PRODUCING GLYCOLIDE KUREHA CORPORATION (JP) 2012-11-15 US disclosed
US-20110263875-A1 Production Process of Glycolide KUREHA CORPORATION (JP) 2011-10-27 US disclosed
EP-2377858-A1 METHOD FOR PRODUCING GLYCOLIDE Kureha Corporation (JP) 2011-10-19 EP disclosed
US-7812181-B2 Process for producing glycolide and glycolic acid oligomer for production of glycolide KUREHA CORPORATION (JP) 2010-10-12 US disclosed
US-20070293653-A1 depolymerizing polyglycolic acid by heating in an organic solvent; system is controlled to suppress efffective concentration of impurities (ammonia, amines or amides, methoxyacetic acid and diglycolic acid); high purity glycolide starting material for polyglycolic acid KUREHA CORPORATION (JP) 2007-12-20 US disclosed
EP-1310496-B1 PROCESS FOR THE PREPARATION OF CYCLIC ESTERS AND METHOD FOR PURIFICATION OF THE SAME KUREHA CORP (JP) 2006-12-06 EP disclosed
US-6916939-B2 Process for the preparation of cyclic esters and method for purification of the same KUREHA KAGAKU KOGYO K.K. (JP) 2005-07-12 US disclosed
US-20030191326-A1 Process for the preparation of cyclic esters and method for purification of the same KUREHA CORPORATION (JP) 2003-10-09 US disclosed
EP-1310496-A1 PROCESS FOR THE PREPARATION OF CYCLIC ESTERS AND METHOD FOR PURIFICATION OF THE SAME KUREHA KAGAKU KOGYO KABUSHIKI KAISHA (JP) 2003-05-14 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20030191326-A1 Process for the preparation of cyclic esters and method for purification of the same CEL, CETP, MCCC2 LTA4H 908/4885ALDH1A1 2201/4885MEN1 3285/4885
US-20110263875-A1 Production Process of Glycolide RPN2, RPN1, DDOST LTA4H 732/4885ALDH1A1 2965/4885MEN1 4593/4885
US-20120289713-A1 METHOD FOR PRODUCING GLYCOLIDE DDOST, MAGT1, UGCG LTA4H 2545/4885ALDH1A1 4614/4885MEN1 2615/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.